摘要
目的探讨急症ICU(EICU)入住患者急性肾损伤(AKI)发病率、临床特征、危险因素及预后。方法回顾性分析2015年7月至2016年7月进入本院急症ICU住院的患者临床资料;使用2012年改善全球肾脏病预后组织(KDIGO)AKI分类标准定义AKI。结果 EICU中AKI发病率为52.2%(106/203),其中1期、2期、3期分别为25.1%、9.4%、17.7%。与非AKI患者比较,AKI患者有更长的住院时间,转出EICU时有更差的肾功能(更高的血肌酐值及更低的估算肾小球滤过率),更多的患者接受肾脏替代治疗,以及更高的住院死亡率。百草枯中毒、机械通气、进入EICU时血肌酐值、脓毒症休克是EICU患者发生AKI的独立危险因素。3期百草枯中毒AKI占全部3期AKI的47%。结论半数以上的EICU患者在入住期间会发生AKI;AKI与EICU患者不良预后相关;百草枯中毒是3期EICU-AKI的重要病因。
Objective To investigate the occurrence and clinical characteristics of acute kidney injury（ AKI） in emergency intensive care unit（ EICU） patients. Methods The patients who enrolled in EICU from July 2015 to July 2016 were retrospectively investigated and analyzed. The AKI was defined by the 2012 Kidney Disease： Improving Global Outcomes（ KDIGO）.Results A total of 203 ICU patients out of 106（ 52.2 %） had AKI; the stage of AKI 1,2,3 are 25. 1%,9. 4%,17. 7%,respectively. Compared to non-AKI patients,AKI patients had worse renal function,higher hospital mortality. Paraquat poisoning,mechanical ventilation,Serum creatinine at ICU admission and Septic Shock were the independent risk factors for AKI in EICU. Stage 3 paraquat-AKI accounted for 47% of all the stage 3 AKI. Conclusions More than half of the EICU patients will have AKI during their hospital stay; AKI has a significant impact on the prognosis of patients in EICU; Paraquat poisoning is an important cause of the stage 3 EICU-AKI.
作者
王玉
唐茜
Wang Yu, et al.(Department of Nephrology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230001, Chin)
出处
《齐齐哈尔医学院学报》
2017年第22期2616-2619,共4页
Journal of Qiqihar Medical University
关键词
ICU
急性肾损伤
流行病学
百草枯中毒
Emergency intensive care unit
Acute kidney injury
Epidemiology
Paraquat poisoning
作者简介
通信作者：唐茜，Email：tangqian723@126．com
