摘要
目的调查心脏机械瓣膜置换术后患者华法林抗凝治疗依从性及其影响因素。方法采用便利抽样法,选取2016年5月至2017年2月于郑州大学第一附属医院心脏外科行心脏机械瓣膜置换术后应用华法林抗凝治疗的185例患者,术后3个月调查其华法林用药知识水平及服药依从性,并探讨华法林抗凝治疗依从性的影响因素。结果心脏机械瓣膜置换术后应用华法林抗凝治疗依从性良好者占75.1%,依从性较差者占24.9%。Logistic回归分析显示,文化程度越高、疾病严重程度越重、华法林用药知识水平越高的患者,华法林抗凝治疗依从性越高。结论心脏机械瓣膜置换术后患者华法林抗凝治疗依从性欠佳,文化程度、疾病严重程度、华法林用药知识水平影响患者华法林抗凝治疗依从性。
Objective To investigate the compliance of warfarin anticoagulant therapy in patients with mechanical cardiac valve replacement and the influencing factors. Methods Using the convenience sampling method, A total of 185 patients with anticoagulation were treated with warfarin for mechanical cardiac valve replacement in the First Affiliated Hospital of ZhenghouUniversity from May of 2016 to February of 2017. The knowledgelevel and medication compliance of warfarin were investigated after three months, and the influencing factors of anticoagulation therapy in patients treated with warfarin were explored. Results 75.1% of patients treated with warfarin anticoagulant after me- chanical cardiac valve replacement had a good compliance and 24. 9% of patients had poor compliance. Logistic regression analy- sis showed that the higher the education level, the heavier the disease severity, the higher the knowledge level of warfarin medica- tion, the higher the compliance with the application of warfarin anticoagulation therapy. Conclusion The clinical application of warfarin anticoagulation therapy in patients with mechanical cardiac valve replacement is poor. The level of education, the severi- ty of the disease, and the level of knowledge of warfarin medication affect the patient＇ s compliance with warfarin anticoagulation therapy.
出处
《河南医学研究》
CAS
2018年第1期15-18,共4页
Henan Medical Research
关键词
心脏瓣膜置换术
抗凝剂
依从性
影响因素
cardiac valve replacement
anticoagulant
compliance
influencing factors
作者简介
通信作者：徐敬，E-mail：xujing00111@sina．com。
