摘要
目的应用药物经济学原理评价3种降压治疗方案,并找出最佳给药方案。方法采用回顾性分析法,收集金华市中心医院120例高血压患者,分为3组,A组给予福辛普利钠片,B组给予缬沙坦胶囊,C组给予苯磺酸氨氯地平,疗程均为8周,观察患者的临床疗效并进行最小成本分析。结果 A、B、C 3组的有效率分别为90.7%、92.3%、92.1%,3组间无显著性差异(P>0.05)。3组的不良反应发生率分别为16.7%、7.7%、13.2%(P>0.05)。3组的人均总成本分别为287.3元、378.7元、320.4元(P<0.05)。结论 3组方案的疗效相似,从经济学角度来说,福辛普利钠(A组)的成本效果比最优。
Objective To compare three different anti-hypertension therapeutic projects by pharmacoeconomic evaluation and to find out the best therapeutic project.Methods Retrospective study was used.120 patients with hypertension were randomly assigned to group A(fosinopril sodium),group B(valsartan),group C(amlodipine besylate tablet),the therapeutic effects were observed and were evaluated by cost minimization analysis.Results The total efficiency of A,B,C group were 90.7%,92.3%,92.1%(P>0.05)respectively.The incidence of adverse reaction were 16.7%,7.7%,13.2%(P>0.05)respectively.The costs were 287.3 yuan,378.7 yuan and 320.4 yuan respectively.Conclution The effectiveness of the three groups was similar.In terms of pharmacoeconomics,group A was the best therapeutic project.
出处
《药学实践杂志》
CAS
2018年第2期189-191,共3页
Journal of Pharmaceutical Practice
基金
金华市中心医院中青年科研启动基金(JY2017-2-13)
关键词
福辛普利钠
缬沙坦
氨氯地平
最小成本分析
fosinopril sodium
valsartan
amlodipine besylate tablet
cost minimization analysis
作者简介
张照伟,硕士研究生,Tel：15058504824,Email：quhaizhijia@163.com
