摘要
目的探讨热毒宁注射液治疗小儿病毒性心肌炎的临床效果,对心肌酶学指标及安全性影响。方法回顾性分析我院收治的病毒性心肌炎患儿65例,随机分成热毒宁注射液组(热毒宁组)23例、利巴韦林组17例、热毒宁联合利巴韦林组(联合组)25例。所有患儿入院后均采用常规的综合治疗,热毒宁组给予热毒宁注射液治疗,利巴韦林组给予利巴韦林注射液治疗,联合组采用前两种药物联合治疗,3组患者的疗程和每天的治疗频率相同。结果利巴韦林组与热毒宁组、联合组相比较,后两组的疗效要好,差异有统计学意义(P<0.05);热毒宁组与联合组比较,疗效差异无统计学意义(P>0.05)。1个疗程结束后,3组患者的心肌酶学指标均比治疗前要好,利巴韦林组的改善情况次于热毒宁与联合组,差异有统计学意义(P<0.05);热毒宁组与联合组的心肌酶学指标改善情况无明显差异(P>0.05)。3种治疗方式均没有出现严重的不良反应。结论热毒宁注射液用于治疗小儿病毒性心肌炎,效果较为显著,且安全性较高。
Objective To investigate the clinical effect, the indexes of myocardial enzymology and its safety of Reduning injection in the treatment of viral myocarditis in children. Methods 65 cases of children with viral myocarditis were randomly divided into the treatment group（ Reduning injection group） of 23 cases, ribavirin group of 17 cases, Reduning injection combined with ribavirin group of 25 cases（ combination group）. All children were admitted to the hospital after the use of conventional comprehensive treatment. Reduning group was treated with Reduning injection. Ribavirin group was treated with ribavirin injection. The combination group received Reduning injection combined with ribavirin injection. Three groups of patients treated the same frequency of treatment each day. Results The curative effect of ribavirin group was better than that of Redunine group and combination group, and the difference was statistically significant（P 0.05）. After one course of treatment, the myocardial enzymes in patients of the 3 groups were better than before treatment, the improvement of the Reduning injection group and the combination group was better than that of the ribavirin group, and the difference was statistically significant（P0.05）. There was no significant difference in the improvement of myocardial enzyme indexes between the Reduning injection group and the combination group（ P 0.05）. None of the three treatments showed any serious adverse reactions. Conclusion Reduning injection in the treatment of viral myocarditis in children has significant curative effect and high safety.
出处
《中国中医药现代远程教育》
2018年第3期92-94,共3页
Chinese Medicine Modern Distance Education of China
关键词
病毒性心肌炎
热毒宁
利巴韦林
心肌酶
心悸
viral myocarditis
Reduning
ribavirin
myocardial enzymology
palpitation
