摘要
葡聚糖是一种细菌分泌的高水溶性天然多糖，具有良好的生物可降解性和相容性。通过化学修饰，可将功能化葡聚糖用做制备不同目的（物质分离、药物缓释和组织工程）水凝胶支架材料。我们综述了近年来葡聚糖水凝胶的物理和化学交联的制备方法，以及葡聚糖水凝胶在组织T程方面的应用，并对其目前存在的问题进行了讨论。
Dextran is a kind of high water - soluble natural polysaccharide, which is secreted by bacteria. The hydrogels prepared by dextran exhibits excellent biocompatiblity and biodegradability. Through modification, dextran could be functionalized and crosslinked, and applied in the fields of substance separation, drug delivery and tissue engineering. This review summarized physical and chemical crosslinking methods of dextran - based hydrogels. Additionally, the applications of tissue engineering field in recent years, the existing problems and the future developments are presented and discussed.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2018年第2期385-388,共4页
Chinese Journal of Experimental Surgery
关键词
葡聚糖
水凝胶
组织工程
Dextran
Hydrogels
Tissue engineering
作者简介
通信作者：李国东，Email：litrue2004@163．com
