摘要
目的探讨社区老年人认知功能障碍与衰弱的关系,为老年人认知功能障碍的防治提供依据。方法2015年6—12月,采用电话联系招募的方式,选取北京市朝阳区三里屯社区卫生服务中心健康管理系统中年龄≥65岁的老年人168例为研究对象。采用一般情况调查表收集老年人临床资料,包括受教育年限、吸烟、饮酒、患病及用药情况;采用微营养评定量表(MNA-SF)评价老年人营养状态;应用加拿大健康与老化研究临床衰弱量表(CFS)进行衰弱评估。采用简易精神状态检查量表(MMSE)评估老年人认知情况,将老年人分为认知功能正常组(106例)和认知功能障碍组(62例)。结果两组年龄、受教育年限、冠心病、高血压、脑卒中、糖尿病检出率、多重用药比例及营养状态比较,差异均有统计学意义(P<0.05)。认知功能障碍组衰弱检出率[37.1%(23/62)]高于认知功能正常组[17.0%(18/106)](P<0.05)。多因素Logistic回归分析显示,经校正年龄、受教育年限、冠心病、高血压、脑卒中、糖尿病、多重用药、营养状态后,衰弱是老年人认知功能障碍的危险因素[OR=3.519,95%CI(1.394,8.886),P<0.05]。结论认知功能障碍的社区老年人衰弱患病率升高,衰弱是社区老年人认知功能障碍的危险因素。
Objective To analyze the relationship between cognitive impairment and frailty in community-dwelling elderly people, so as to provide a reference for the prevention and treatment of the disease in such a population. Methods By the telephone recruitment, we enrolled 168 participants aged ≥ 65 years registered in the health management system of Sanlitun Community Health Service Center in Chaoyang District, Beijing from June to December 2015. They were surveyed by a Baseline Characteristics Questionnaire involving the clinical data such as years of schooling, smoking prevalence, alcohol prevalence, medical history and drug treatment history, and by the Chinese version of short-form Mini Nutritional Assessment（MNA-SF） for assessing the status of nutrition, and the Chinese version of Canadian Study of Health and Aging-clinical Frailty Scale（CSHA-CFS） for assessing the status of frailty, and Mini-mental State Examination（MMSE） for assessing the status of cognitive function. Based on the assessing results of cognitive function, the participants were divided into normal cognitive function group（n=106） and cognitive impairment group（n=62）. Results Two groups had significant differences in terms of age distribution, years of schooling, coronary heart disease prevalence, hypertension prevalence, stroke prevalence, diabetes mellitus prevalence, polypharmacy prevalence and status of nutrition（P〈0.05）. The prevalence of frailty was significantly higher in the cognitive impairment group than in the normal cognitive function group [37.1%（23/62） vs. 17.0%（18/106）]（P〈0.05）. Multivariate Logistic regression analysis found that, frailty was the risk factor for cognitive impairment after adjusting for age, years of schooling, coronary heart disease, hypertension, stroke, diabetes mellitus, polypharmacy and status of nutrition[OR=3.519, 95%CI（1.394,8.886）,P〈0.05]. Conclusion Increased prevalence of frailty is found in community-dwelling elderly people with cognitive impairment. Frailty may be considered as the risk factor for cognitive impairment in such a population.
出处
《中国全科医学》
CAS
北大核心
2018年第2期185-189,共5页
Chinese General Practice
基金
2015年首都全科医学研究专项课题(15QK12)
关键词
认知障碍
衰弱
老年人
社区
Cognitive disorders
Frailty
Aged
Community
作者简介
通信作者：孙倩美,主任医师;E-mail：sunqianmei5825@163.com
