摘要
目的 评价分析奥卡西平与碳酸锂治疗躁狂症的疗效差异。方法 通过数据检索，对10项奥 卡西平与碳酸锂治疗躁狂症的研究资料进行Meta分析，评价有效率的差异和症状改善的差异。结果 在 有效率方面，奥卡西平与碳酸锂治疗躁狂症的有效率差异无统计学意义（Z=0.10，P=0.92）。在症状学评 价方面，奥卡西平与碳酸锂治疗躁狂症的症状评分差异无统计学意义（Z=0.26，P=0.79）。结论 奥卡西 平与碳酸锂治疗躁狂症的疗效相似。
ptom improvement were assessed by retrieving database, and a total of 10 items of research data about manic treatment with oxcarbazepine and lithium carbonate were analyzed. Results Through heterogeneity test（ χ2=1.89, df=9, P=0.98, I2=0%）, by using the fixed effect model（ WMD=1.02, 95%CI=0.72-1.45,Z=0.10, P=0.92）, it suggested that there was no significant difference in the effective rate of oxcarbazepine and lithium carbonate in the treatment of mania. Through heterogeneity test（ χ2=177.15, df=32, P 〈 0.01,I2=81.9%）, by using random effect model（ WMD= -0.03, 95%CI=-0.25-0.19,Z=0.26,P=0.79）, it suggested that there was no significant difference in symptom score of treating mania with oxcarbazepine and lithium carbonate. Conclusions The effect of oxcarbazepine and lithium carbonate may be similar in the treatment of mania.
出处
《神经疾病与精神卫生》
2017年第10期739-742,共4页
Journal of Neuroscience and Mental Health
作者简介
通讯作者：金卫东Email：wdjin@163．com
