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再生障碍性贫血的诊断与鉴别诊断 被引量:2

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摘要 再生障碍性贫血(AA)是由多种病因及不同发病机制引起的一种骨髓造血功能衰竭性疾病,主要表现为骨髓有核细胞增生低下、外周全血细胞减少以及由此导致的贫血、出血和感染等临床表现。其发病机制尚未完全阐明,目前认为T淋巴细胞异常活化及功能亢进导致骨髓造血干细胞损伤和凋亡过度在获得性AA发病机制中占主要地位,这也是应用免疫抑制治疗(IST)获得性AA的理论基础。我们结合自身的临床经验及科研体会,重点解析AA的诊断思路。
作者 刘春燕 付蓉
出处 《临床内科杂志》 CAS 2017年第12期797-799,共3页 Journal of Clinical Internal Medicine
作者简介 通讯作者:付蓉,E-mail:florai@vip.sina.com.cn
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