摘要
目的了解在新的治疗策略扩大之际,广州市尚未开始抗病毒治疗的艾滋病病毒(human immunodeficiency virus,HIV)阳性者的抑郁症和焦虑症现状,并按感染时间分层分析社会支持、社会歧视和自我歧视对其的影响作用。方法在广州市六个区对尚未开始抗病毒治疗的HIV阳性者进行横断面调查,收集调查对象的社会人口学特征,HIV相关健康状况,抑郁,焦虑,从外界领悟的社会支持、社会歧视及自我歧视情况信息,以抑郁和焦虑分别做因变量,其他信息做自变量进行二分类Logistic回归分析。结果 452名调查对象中,66.2%(299/452)和52.9%(239/452)的阳性者分别被评定为抑郁和焦虑。多因素分析结果显示,在感染时间<1个月的阳性者中,家庭支持(OR=0.80,95%CI:0.63~1.00,P=0.049)与自我歧视(OR=2.15,95%CI:1.36~2.44,P=0.001)会影响抑郁,重要他人支持(OR=0.68,95%CI:0.53~0.87,P=0.003)和自我歧视(OR=2.31,95%CI:1.55~3.43,P<0.001)会影响焦虑;在感染时间≥1个月的阳性者中,自我歧视(OR=2.72,95%CI:1.74~4.25,P<0.001)会影响焦虑。结论广州市的HIV阳性者存在较高的抑郁和焦虑患病率,自我歧视是影响焦虑和抑郁发生的重要因素,不同来源支持对不同感染时间的HIV阳性者的抑郁和焦虑的影响作用不同,故应针对性地提供社会支持。
Objective To investigate tiae mental health status among PLWH （people living with HIV/AIDS） who had not started ART before in Guangzhou Under the ART expansion era and to analyze the association between social support, social stigma and self-stigma with depression and anxiety in different time since confirmation of HIV infection, respectively. Methods A cross-sectional survey was conducted in 6 districts of Guangzhou. Data were collected on demographic characteristics, HIV-related health status, depression status, anxiety status, perceived social support, perceived social stigma and self-stigma of HIV positive participants. To investigate the influencing factors of depression and anxiety, respec- tively, Logistic regression analysis were applied to identify their assoeiafions. Results Of the 452 participants, the de- pression detection rate was 66. 2% （299/452） and the anxiety detection rate was 52. 9% （239/452）. Multivariate logistic regression analysis revealed that, among EL^H with less than 1 month since confirmation of HIV infection, family support （ OR = O. 80, 95 % Cl：O. 63-1.00, P =~O. 049 ）and se[f-stigma （ OR = 2. 15, 95 % CI： h 36-2.44, P = 0. 001 ） were signif- icantly associated with depression, sigmfieant others support（ OR = 0. 68, 95% CI：0. 53-0. 87 P=0. 003 ） and seff-stigma （ OR = 2. 31, 95% Cl： 1.55-3.43, P.〈 0. 001） were significantly associated with anxiety; among PLWH with 1 month or of more since confirmation of HIV mfection, self-stigma（ OR = 2. 72, 95% CI： 1. 74-4： 25, P 〈 0. 001 ） was significantly associated with anxiety. Conclusions Depression and anxiety are common amgpg ,people living with HIV/AIDS who had not started ART in Guangzhou. Self-stigma is an important influencing factor of anxiety and depression. Different source of sup- ports have different effect toward depression and anxiety among PLWH iniMiff, renf.time since conf4rmation of HIV infection; so the social support should be targeted to provide for PLWH.
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2017年第12期1214-1218,共5页
Chinese Journal of Disease Control & Prevention
基金
广州市科学(技术)研究专项(201607010368)
关键词
HIV
抑郁
焦虑
HIV
Depression
Anxiety
作者简介
杜璇（1991-），女，广东梅州人，在读硕士研究生。主要研究方向：艾滋病有关高危人群研究。;【通讯作者】顾菁，E-mail：gujing5@mail．sysu．edu．cn．
