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经颅直流电刺激对非流利型原发性进行性失语症的治疗作用 被引量:4

Therapeutic Effect of Transcranial DC Stimulation on Non-Fluative Primary Progressive Aphasia
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摘要 目的了解经颅直流电刺激结合语言训练相比单纯语言训练对非流利型原发性进行性失语症的治疗作用,为临床应用提供理论依据。方法选择2014年12月~2016年9月我院40例非流利型原发性进行性失语症患者进行临床对照研究,随机分为实验组和对照组,每组20例,比较两组患者治疗前和治疗60天后汉语失语检查(aphasia battery in china,ABC)评分、语言检测、日本生活交流能力(communication activities daily living,CADL)评分的差异。结果两组患者治疗前后ABC评分存在差异(F=31.458,P<0.001),不同时点存在差异(F=126.984,P<0.001),时间与分组存在交互作用(F=36.402,P<0.001);治疗60天后,两组患者语言检测结果中听词-图匹配、图命名、词朗读、词复述指标均有明显提高,实验组更为明显;治疗后两组患者日常生活交流能力构成的差异有统计学意义(χ~2=14.200,P=0.007)。治疗前后比较,两组患者脑电和肌电监测到的波幅均有明显升高,频率有一定降低,治疗后脑电(Z=23.475,F=0.000)、肌电(Z=5.147,P=0.000)监测结果的差异显著(F<0.05)。结论经头颅进行直流电刺激结合语言训练的方式治疗非流利型原发性进行性失语症的临床治疗效果较好,能显著改善患者的汉语失语状况,同时改善患者日常生活交流能力。 Objective To understand the therapeutic effect of transcranial DC stimulation combined with language training and simple language training on non-fluative primary progressive aphasia, and to provide theoretical experience for the clinical application of rehabilitation. Methods From December 2014 to September 2016, 40 patients with non-fluogenic primary progressive aphasia induced by cerebral infarction were enrolled in this study. They were divided into two groups: the experimental and control groups. Twenty patients were compared between the two groups before and after treatment for 60 days after ABC score, language test, CADL score difference. Results There was a significant difference between the two groups(P〈0.001 ), and the time difference between the two groups was statistically significant (P〈0.001). After 60 days of treatment, the two groups of patients were significantly improved in the language test results, and the experimental group was more obvious. There was a significant difference in the composition of daily life communication between the two groups (P〈0.05). Compared before and after treatment, two groups of patients with brain electricity and muscle electricity monitoring to the volatility has increased significantly, reduce the frequency to a certain extent, compared two groups, two groups of comparison, therapy, electricity(P〈0.05), electromyographymonitoring results of significant difference(P〈0.05). Conclusions The treatment of non - fluative primary progressive aphasia by the combination of DC stimulation and language training is better, and can significantly improve the patient's aphasia and the ability of daily life communication.
出处 《中国听力语言康复科学杂志》 2017年第6期449-452,共4页 Chinese Scientific Journal of Hearing and Speech Rehabilitation
关键词 直流电刺激 语言训练 非流利型原发性进行性失语症 DC stimulation Language training Nonfluent variant primary progressive aphasia
作者简介 邓静本科主管技师;研究方向:言语治疗和作业治疗,通讯作者:邓静,E—mail:1290848689@qq.com
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