摘要
目的 系统评价肺段与肺叶切除术对早期肺癌术后肺功能的影响.方法 检索中国生物医学文献数据库、中国知网、万方数据库及维普中文科技期刊数据库,PubMed、Medline、EMBASE、Cochrane图书馆等数据库,检索时间均从建库至2016年9月30日.收集有关肺段与肺叶切除术对早期肺癌治疗的文献,根据Cochrane系统评价员手册推荐的方法行文献质量评价,效应量以WMD及其95％ CI表示,采用RevMan 5.3软件进行meta分析.结果 共纳入文献8篇,患者694例,其中肺段切除术患者308例,肺叶切除术患者386例.结果显示,肺段与肺叶切除术FVC％（MD=9.91,95％CI：3.53～ 16.30,P =0.002）、术后/术前FVC％百分比（MD=6.74,95％CI：5.52～ 7.79,P＜0.05）、FEV1％ （MD=13.25,95％CI：10.25～ 16.26,P＜0.05）和术后/术前FEV 1％百分比（MD=7.18,95％CI：5.88～ 8.48,P＜0.05）差异有统计学意义.结论 早期肺癌患者行肺段切除术后肺功能指标优于肺叶切除术,肺段切除术更有利于保留患者肺功能.
Objective To systemic evaluate postoperative pulmonary function between segmentectomy and lobectomy in patients with early stage non-small cell lung cancer.Methods Computer searched was performed up to September 2016 at the Cochrane Library,PubMed,EMBASE,CBM,CNKI,VIP and Wanfang database,collected postoperative pulmonary function between segmentectomy and lobectomy in Patients with early stage Non-Small Cell Lung Cancer.Study selection,data collection and critical assessment of the included studies were performed according to the recommendations of the Cochrane Collaboration.Results Eight studies included 308 segmentectomy and 386 lobectomy were identified for inclusion.FVC% （MD =9.91,95% CI：3.53-16.30,P =0.002）,postoperation / preoperation FVC% （MD =6.74,95% CI：5.52-7.79,P 〈0.05）,FEV1% （MD =13.25,95% CI：10.25-16.26,P 〈 0.05）,postoperation / preoperation FEV1% （MD =7.18,95 % CI：5.88-8.48,P 〈 0.05） showed significant difference.Conclusion Pulmonary function index was superior to lobectomy after segmentectomy in patients with early stage lung cancer,and segmentectomy resection was more beneficial to preserve lung function.
出处
《中华胸心血管外科杂志》
CSCD
2017年第9期534-538,共5页
Chinese Journal of Thoracic and Cardiovascular Surgery
关键词
肺癌
肺段切除术
肺叶切除术
肺功能
Lung cancer
Segmentectomy
Lobectomy
Pulmonary function
作者简介
通信作者：李印Email：rhjy86@163．com.
