摘要
目的:建立理气颗粒的质量标准。方法:采用薄层色谱法对制剂中的丹参、当归和大黄进行薄层鉴别,采用高效液相色谱法对理气颗粒中丹酚酸B进行含量测定。结果:薄层色谱斑点清晰,阴性对照无干扰;丹酚酸B在17.80~106.8μg/m L之间线性关系良好(r=0.999 6),精密度、稳定性、重复性试验的RSD<2%,平均回收率为97.31%(RSD=2.627%)。结论:该方法稳定、简单、准确,可作为理气颗粒的质量控制标准。
Objective： To establish the quality standard for LiQi granules. Methods： Dan Shen（salvia miltiorrhiza）, Dang Gui（Angelica sinensis） and Da Huang（rheum officinale） in the preparations were identified by using TCL, the contents of Salvianolic Acid B in LiQi granules were detected by adopting HPLC. Results： The spots of TLC were clear and no interference was found in the negative control; Salvianolic Acid B showed better linear relationship in the range between 17.80 and 106.80 μg/m L（r=0.999 6）, RSDs of precision, stability and repeatability were less than 2%, mean average recovery was 97.31%（RSD=2.627%）. Conclusion： The method, stable, simple and accurate, could be used as the standard of quality standard for LiQi granules.
出处
《西部中医药》
2017年第9期52-54,共3页
Western Journal of Traditional Chinese Medicine
基金
南通市青年医学人才科研基金项目(编号WQ2014041)
作者简介
张锦林（1977-）,男,副主任药师.研究方向：医院药学.
通讯作者：季屹红（1979-）,女,副主任药师.研究方向：医院药学.
