摘要
目的探讨外周血CD64指数及降钙素原(PCT)在急性心力衰竭合并肺部感染诊断中的价值。方法 96例急性心力衰竭患者,根据是否合并肺部感染分为感染组50例及非感染组46例;另选取45例健康体检者作为对照组。比较3组CD64指数及PCT水平,并分析CD64指数及PCT水平与急性心力衰竭合并肺部感染的相关性。采用受试者工作特征(ROC)曲线法分析CD64指数及PCT水平诊断急性心力衰竭合并肺部感染的效能。结果感染组CD64和PCT水平高于非感染组和对照组(P<0.05);CD64指数、PCT水平与急性心力衰竭患者合并肺部感染均呈正相关(均P<0.05)。ROC曲线分析结果显示,CD64指数和PCT诊断急性心力衰竭合并肺部感染的ROC曲线下面积分别为0.870和0.876,敏感度分别为84.0%、82.0%,特异度分别为87.0%、89.1%。结论在急性心力衰竭患者中,CD64指数和血清PCT水平可作为诊断肺部感染的有效指标。
Objective To explore the value of peripheral blood CD64 index and procalcitonin （PCT） in the diagnosis of acute heart failure complicated with pulmonary infection. Methods A total of 96 patients with acute heart failure were divided into infection group（ n = 50） and non-infection group （n = 46 ） according to whether complicated with pulmonary infection, another 45 healthy subjects undergoing physical examination as control group. CD64 index and PCT level were compared among the three groups. The correlation of CD64 index or PCT level with pulmonary infection was analyzed among patients with acute heart failure. Receiver operating characteristic （ROC） curve was used to analyze the diagnostic efficiency of CD64 index and PCT level for acute heart failure complicated with pulmonary infection. Results CD64 index and PCT level in the infection group were higher than those in the non-infection group and control group （ P 〈 0.05 ）. CD64 index and PCT level positively correlated with pulmonary infection among patients with acute heart failure（ all P 〈 0.05 ）. The result of ROC curve analysis showed that the areas under the curve of CD64 index and PCT for diagnosis of acute heart failure complicated with pulmonary infection were 0. 870 and 0. 876 respectively, the sensitivities were 84. 0% and 82. 0% respectively, and the specificities were 87.0% and 89.1% respectively. Conclusion CD64 index and serum PCT level could act as effective indicators for diagnosing pulmonary infection among patients with acute heart failure.
作者
张红英
张宁宁
李新强
宗媛
ZHANG Hong-ying ZHANG Ning-ning LI Xin-qiang ZONG Yuan(Intensive Care Unit,Shaanxi Provincial People＇s Hospital,Xi＇an 710068 ,China Department of Function,Xi＇an North Hospital,Xi＇an 710043 ,China)
出处
《广西医学》
CAS
2017年第10期1515-1517,共3页
Guangxi Medical Journal
关键词
急性心力衰竭
肺部感染
降钙素原
CD64指数
诊断
合并症
Acute heart failure, Pulmonary infection, Procalcitonin, CD64 index, Diagnosis, Complication
作者简介
张红英（1982-），女，硕士，主治医师，研究方向：急危重症疾病的诊治及研究。电子邮箱：869239415@qq．com
通信作者：宗媛（1973-），女，本科，副主任医师，研究方向：急危重症疾病的诊治及研究，电子邮箱：854119178@qq．com。
