摘要
目的运用Meta分析的方法比较腹腔镜与开腹胃癌术后炎性因子的比较。方法主题词检索Cochrane Library、Pub Med、和万方数据数据库、中文科技期刊全文数据库、EMBASE、CNKI、数字化期刊全文数据库和中国期刊全文数据库,检索时间2012—2016年已公开发表的腹腔镜与传统开腹胃癌根治术后炎性因子随机对照研究,对纳入的文献进行质量评价,利用Revman5.2软件对术后各炎性因子进行Meta分析。结果最终筛选纳入8项研究,共675例胃癌患者,包括腹腔镜组322例,开腹组353例,Meta分析结果显示,腹腔镜组患者IL-6、IL-8、CRP和TNF-α水平均显著低于开腹组患者,差异均有统计学意义(P<0.05)。结论腹腔镜组术后的炎性指标低于传统开腹组,对机体的创伤刺激反应较小,有利于术后病情康复。
Objective To compare the postoperative inflammatory factors of laparoseopie and open stomach cancer by meta-analysis. Methods The literatures of randomized controlled study of inflammatory factors after laparoscopic and conventional open stomach cancer were collected from 2012 to 2016. The quality of the literature was evaluated and the postoperative inflammatory factors were analyzed by RevmanS.2 analysis software. Results A total of 6 studies were selected and the total number of samples was 675, including 322 eases of laparoscopic group and 353 cases of laparotomy. Meta-analysis showed that laparoscopic group and laparotomy group IL-6 , IL-8, CRP, TNF-a were statistically significant, laparoscopic group values were lower than the laparotomy group, the differences were statistically significant （P〈0.05）. Conclusions The inflammatory indexes in the laparoscopic group were lower than those in the traditional laparotomy group, and the response to the trauma was less, which is beneficial to the rehabilitation of the patients after the operation.
作者
李阳
张义胜
赵军
赵海远
徐冉
Li Yang et al(The First Affiliated Hospital （ Yifishan Hospital） of Wannan Medical College, Wuhu 241000, China)
出处
《齐齐哈尔医学院学报》
2017年第14期1636-1638,共3页
Journal of Qiqihar Medical University
关键词
胃肿瘤
炎性因子
腹腔镜
META分析
Stomach neoplasms
Inflammatory factors
Laparoscopy
Meta analysis
作者简介
通信作者：张义胜，Email：youngleeDoc@163．com
