摘要
目的研究重症监护病房患者导管相关性感染的危险因素及其临床防治措施,为临床治疗提供参考依据。方法选取2014年10月-2016年12月医院重症监护病房收治的695例采用留置导管的患者进行研究,分析重症监护病房住院患者导管相关性感染的发生情况,以及感染病原菌的分布和危险因素,并总结相应的防治措施。结果 695例患者中发生感染的患者共103例,感染率为14.82%;共检出病原菌154株,主以革兰阴性菌为主,共83株占53.90%;logistic多元回归分析显示,年龄≥60岁、急性生理与慢性健康评分(APACHEⅡ评分)≥17分、血清白蛋白含量<30g/L、入住重症监护病房时间≥14d,导管留置时间≥7d,合并基础疾病均是患者发生导管相关性感染的独立危险因素(P<0.05)。结论重症监护病房患者发生导管相关性感染的主要病原菌为革兰阴性菌,诱发患者发生感染的危险因素较多,临床治疗过程中应根据相应情况给予具体的防治措施以减少该类患者的感染。
OBJECTIVE To investigate the risk factors and clinical preventive measures of catheter-related infections in intensive care unit patients , so as to provide references for clinical treatment.METHODS A total of 695 patients with indwelling catheters were enrolled in our hospital from Oct.2014 to Dec.2016.The incidence of catheter-related infections in hospitalized patients and the distribution and risk factors of pathogens were analyzed, and the corresponding prevention and control measures were summarized.RESULTS A total of 103 patients were infected in 695 patients, and the infection rate was 14.82%.Totally 154 strains of pathogenic bacteria were detected, which were mainly 83 strains of gram-negative bacteria, accounting for 53.90%.Multivariable logistic regression analysis showed that age ≥60 years old, APACHEⅡ score≥17, serum albumin content 〈30 g/L, stay in intensive care unit ≥14 d, catheter retention time ≥7 d and combination with underlying diseases were independent risk factors for patients with catheter-related infections （P〈0.05）.CONCLUSION The main pathogens of catheter-related infections in intensive care unit patients are gram-negative bacteria, and there are many risk factors for infections, so the clinical treatment should be based on the corresponding circumstances to give specific measures to reduce the infections in patients.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2017年第16期3692-3694,3702,共4页
Chinese Journal of Nosocomiology
基金
浙江省医药科技基金资助项目(2014-3-071)
关键词
重症监护病房
导管置入
感染
危险因素
Intensive care unit
Catheterization
Infection
Risk factors
