摘要
目的探讨甲状腺良恶性结节实时超声造影（contrast-enhanced ultrasound，CEUS）误诊原因及甲状腺结节大小及钙化情况对CEUS结果的影响．以提高甲状腺疾病诊断准确率。方法以病理结果作为金标准对331例甲状腺疾病患者的421个结节的CUES图像特点进行回顾性分析。结果421个结节中33个结节性甲状腺肿误诊为TC，8个结节性甲状腺肿误诊为甲状腺腺瘤，8个TC误诊为结节性甲状腺肿，2个TC误诊为甲状腺腺瘤，CEUS对甲状腺良恶性病变诊断的正确率达87．89％，误诊率达12．11％。甲状腺结节的大小及钙化情况对诊断准确率有影响，其中长径〈10mm组误诊率与其他2组相比明显偏高，差异具有统计学意义（P〈0．05），粗大钙化组的误诊率与微钙化组相比明显偏高，差异具有统计学意义（P〈0．05）。结论结节大小及结节钙化情况对CEUS诊断准确率均有影响．分析误诊原因有利于进一步提高对CEUS的认识水平。
Objective To investigate the reason for misdiagnosis of real-time contrast-enhanced ultrasound （CEUS） in identifying benign and malignant thyroid nodules and the impact of nodule size and calcification on CEUS result. Methods Retrospective analysis were carried out in 331 cases of thyroid disease patients with 421 nodules. All the nodules were performed CEUS and confirmed by pathology. Results In the total of 421 nodules, 33 nodular goiters were misdiagnosed as thyroid carcinoma. 8 nodular goiters were misdiagnosed as thyroid adenoma. 8 thyroid carcinomas were misdiagnosed as nodular goiter, 2 thyroid carcinomas were misdiagnosed as thyroid adenoma. The accuracy of diagnosis for thyroid benign and malignant lesions by CEUS was 87.89%, and the mis- diagnosis rate was 12.11%. The size of the thyroid nodule and the form of calcification had influence on diagno- sis. In the group with diameter of the nodule less than 10 ram, the misdiagnosis rate was higher compared with the other two groups, and the difference was statistically significant （P〈0.05）. In addition, the misdiagnosis rate in the group with bulky calcification was higher than microcalcifications group, and the difference was statistically significant （P〈0.05）.Conclusion The size of the thyroid nodule and the form of calcification have some impact on diagnosis of CEUS. To make clear the reason for misdiagnosis is beneficial to improve the diagnostic level of thyroid diseases.
出处
《中华内分泌外科杂志》
CAS
2017年第4期307-310,共4页
Chinese Journal of Endocrine Surgery
基金
陕西省社会发展科技攻关项目（2015SF100）
关键词
超声造影
甲状腺结节
甲状腺癌
钙化
Contrast-enhanced Ultrasound
Thyroid nodules
Thyroid carcinoma
Calcification
作者简介
通信作者：周琦，Email：13909232905@163．com
