摘要
肝吸虫病是一种重要的人兽共患寄生虫病,也是我国重点防治主要食源性寄生虫病之一。肝吸虫感染被国际癌症研究中心(IARC)确定为Ⅰ类致癌因素,其所致胆管癌是肝吸虫感染的严重后果之一。本文就目前国内外肝吸虫感染的流行病学及其诱发胆管癌的发病机制研究进展和成果做一综述,为今后学者进一步深入研究肝吸虫病提供参考资料。
Liver fluke disease is one of important zoonotic parasitic diseases,and is also one of the major food-borne parasitic diseases in China.Liver fluke infection was determined as a class I carcinogen by International Agency for Research on Cancer（IARC）.Cholangiocarcinoma is a serious consequence of the infection.This paper summarizes the results of the studies on epidemiology of liver fluke infection and pathogenesis of cholangiocarcinoma caused by the infection,in order to provide a reference for further researches on liver fluke disease.
作者
吴海燕
隋春兴
王爱秋
王红梅
任一鑫
WU Haiyan SUI Chunxing WANG Aiqiu WANG Hongmei REN Yixin(Department of Oncology , the People＇s Hospital of Lyushun Kou District, Dalian , Liaoning 116041, China)
出处
《中国微生态学杂志》
CAS
CSCD
2017年第7期866-868,F0003,共4页
Chinese Journal of Microecology
关键词
肝吸虫
胆管癌
发病机制
炎症反应
氧化应激
Liver fluke
Cholangiocarcinoma
Pathogenesis
Inflammatory reaction
Oxidative stress
作者简介
吴海燕（1984-），女，主治医师，主要从事肿瘤防治研究工作，E—mail：angela—felix@163．com
通信作者：任一鑫，E—mail：renyixin1980@126．com
