摘要
目的探讨严格血糖控制对全身炎症反应综合征患者腹部术后CRP、PCT及术后并发症的影响。方法方便选择2016年1—12月间该院普通外科收治的伴全身炎症反应综合征行腹部手术的患者71例,随机分为2组,实验组为严格控制血糖组37例,手术后开始行胰岛素持续静脉泵入治疗,将血糖严格控制4.4~7.8 mmol/L;对照组为常规控制血糖组34例,仅当患者血糖>11.1 mmol/L时给予胰岛素治疗。观察两组患者术后当日、术后1 d、术后3 d、术后7 d PCT、CRP、术后并发症等指标。结果两组患者的一般情况比较差异无统计学意义。两组患者手术当日CRP水平均明显升高,手术第1天开始实验组由(32.83±6.43)下降至(17.61±4.15),较对照组下降明显;实验组血清PCT水平在48 h内由(2.75±1.38)下降至(1.53±1.56),差异有统计学意义(P<0.05)。实验组术后并发症发生率明显低于对照组。结论严格控制血糖可降低SIRS行腹部手术患者血清CRP、PCT水平,减少手术并发症的发生,改善预后。
Objective To observe the effect of strict blood glucose control on the CRP, PCT and postoperative complications of patients with systemic inflammatory response syndrome after the abdominal operation. Methods Convenient selection 71 cases of patients with systemic inflammatory response syndrome after the abdominal operation admitted and treated in our hospital from January to December 2016 were selected and randomly divided into two groups and divided into two groups,the experimental group were 37 cases with strict blood glucose control, and adopted the continuous intravenous pump treatment of insulin, and the blood glucose was strictly controlled in 4.4-7.8 mmol/L, while the control group were 34 cases with routine blood glucose control, and the patients were treated with insulin when the patients＇ blood glucose 11.1mmol/L,and the PCT, CRP and postoperative complications immediately, 1 d, 3 d and 7 d after operation of the two groups were observed. Results The difference in the general situation between the two groups was not statistically significant, and the CRP level of the two groups on the very day of operation obviously increased and the CRP level at 1 d after surgery in the experimental group decreased from（32.83±6.43） to（17.61±4.15）, and the decrease was obvious compared with that in the control group, and the serum PCT level in 48 h in the experimental group decreased from（2.75±1.38） to（1.53±1.56）, and the difference was statistically significant（P〈0.05）, and the incidence rate of complications after operation in the experimental group was obviously lower than that in the control group. Conclusion The strict control of blood glucose can reduce the serum CRP and PCT levels of patients with abdominal operation and reduce the occurrence of operation complications and improve the prognosis.
出处
《中外医疗》
2017年第18期28-30,共3页
China & Foreign Medical Treatment
关键词
严格血糖控制
全身炎症反应综合征
腹部手术
炎症状态
Strict control of blood glucose
Systemic inflammatory response syndrome
Abdominal operation
Inflammatory state
作者简介
何锋（1981-）,男,甘肃酒泉人,本科,主治医师,研究方向院外科.
