摘要
目的 对B超监测下稽留流产清宫术后服用屈螺酮炔雌醇片,预防宫腔粘连的临床效果进行探讨.方法 将216例B超监测下行稽留流产清宫术研究对象设为对照组108例,术后采取常规治疗;研究组108给予常规治疗、屈螺酮炔雌醇片治疗.比较2组术后情况,治疗后1个月内宫腔粘连情况,治疗1年后的再孕、不孕、流产情况.结果 研究组阴道出血时间、盆腔积液及月经复潮时间均显著低于对照组,差异均有统计学意义（t=6.114,t=9.481,t=9.201,P〈0.05）;研究组子宫内膜厚度明显大于对照组,差异均有统计学意义（t=14.171,P〈0.05）.对照组治疗后1周、2周等子宫粘连比例均显著高于研究组,差异均有统计学意义（χ2=5.329,χ2=6.051,P〈0.05）.2组治疗1年后的再孕率比较,差异无统计学意义（χ2=0.113,P〉0.05）;对照组和研究组治疗1年后的不孕率、流产率进行比较,对照组明显高于研究组,差异均有统计学意义（χ2=4.317,χ2=5.225,P〈0.05）.结论 B超监测下稽留流产清宫术后立即服用屈螺酮炔雌醇片,能够有效预防术后宫腔粘连,并且减少流产、不孕等并发症,可根据患者实际情况进行应用.
Objective To discuss clinical efficacy of taking drospirenone and ethinylestradiol tablets in preventing intrauterine adhesion after missed abortion curettage with b-ultrasonic observation.Methods216 cases of study objects provided with missed abortion curettage with b-ultrasonic observation were divided into control group with 108 cases and research group with 108 cases.Patients in control group were provided with conventional treatment after surgery, while those in research group were provided with conventional treatment and drospirenone and ethinylestradiol tablets.Two groups were compared for condition after surgery such as intrauterine adhesion in 1month after treatment, secondary pregnancy, infertility and abortion in 1 year after treatment.ResultsTime of vaginal bleeding, pelvic effusion and time of return of menses in research group were significantly lower than those in control group, with difference having statistical significance （t=6.114,t=9.481,t=9.201,P〈0.05）.Endometrial thickness of research group was distinctly greater than control group, with difference having statistical significance （t=14.171,P〈0.05）.In 1 week and 2 weeks after treatment, the proportion of uterus adhesion in control group was higher than that in research group, with difference having statistical significance （χ2=5.329,χ2=6.051,P〈0.05）.The difference in rate of secondary pregnancy in 1 year after treatment between two groups had no statistical significance （χ2=0.113,P〉0.05）.In the case of infertility rate and rate of abortion in 1 year after treatment, control group was higher than research group with difference having statistical significance （χ2=4.317,χ2=5.225,P〈0.05）.ConclusionTaking drospirenone and ethinylestradiol tablets after missed abortion curettage with b-ultrasonic observation can effectively prevent intrauterine adhesion, which can also reduce complications such as abortion and infertility, therefore, it shall be applied in accordance with specific condition of patients.
作者
朱长远
ZHU Chang-yuan(Jinhua Hospital of traditional Chinese Medicine, Jinhua 321000, China)
出处
《中国生化药物杂志》
CAS
2017年第6期183-184,187,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
B超监测
稽留流产
屈螺酮炔雌醇片
宫腔粘连
B-ultrasonic observation
missed abortion curettage
drospirenone and ethinylestradiol tablets
intrauterine adhesion
作者简介
朱长远，通信作者，男，硕士，主治医师，研究方向：B超，E-mail：bchaoys001@126．com。
