摘要
目的探讨多层螺旋CT三维(3D)重建技术在肺癌诊断及淋巴转移预测中的应用及其价值。方法以2013年3月至2015年12月间进行手术的肺癌患者86例作为研究对象,所有患者均于术前接受多层螺旋CT扫描并经图像后处理工作站进行3D重建。回顾性分析影像学与术后病理学检测结果的符合程度,判断其对肺癌辅助诊断及淋巴结转移的预测价值。结果多层螺旋CT三维重建对86例肺癌的成像结果显示,除细支气管征及空泡征外,3D成像肺癌典型征象显示率高于轴位成像(P均<0.01)。3D成像对淋巴结转移诊断的敏感度、特异度及准确度分别为93.44%、80.00%及89.53%,轴位成像的敏感度、特异度及准确度分别为73.77%、60.00%及69.77%,差异均有统计学意义(P均<0.05)。3D成像对淋巴结转移诊断效能明显优于轴位成像。3D图像转化为2D图像显示,有淋巴结转移的患者肿瘤血管密度明显高于无淋巴结转移患者[(0.07±0.04)vs(0.04±0.01),P<0.05]。结论多层螺旋CT三维重建对肺癌辅助诊断及淋巴转移预测具有良好的应用价值。
Objective To explore the value of multi-slice spiral computed tomography （MSCT） three-dimensional （3D） reconstruction technique in diagnosis of lung cancer and prediction of lymph node metastasis. Methods Eighty-six patients with lung cancer who underwent operation between March 2013 and December 2015 were selected as research objects. All patients received MSCT scanning, and its result was processed for 3D reconstructions by image post-processing workstation. The conformity degree between imaging and postoperative pathological examination was analyzed retrospectively to evaluate the value of the 3D imaging for lung cancer diagnosis and prediction of lymph node metastasis. Results MSCT 3D imaging in 86 patients with lung cancer showed that compared with axial imaging, the display rates of lung cancer typical signs significantly increased （ all P 〈 0.01 ） except for the bronchial sign and vacuolar sign, and the sensitivity （ 73.77% vs 93.44% ） ,specificity （60.00% vs 80.00% ） and accuracy （69.77% vs 89.53% ）for lymph node metastasis increased in 3D imaging（ all P 〈 0. 05 ）, so 3D imaging was superior to axial imaging for the diagnostic efficacy of lymph node metastasis. The 2D image transformed from 3D image displayed that the tumor vascular density in patients with lymph node metastasis was significantly higher than that in patients without lymph node metastasis （0.07 ±0.04 vs 0. 04 ± 0. 01, P 〈 0. 05 ）. Conclusion The 3D reconstruction of MSCT has good application value in the auxiliary diagnosis of lung cancer and the prediction of lymph node metastasis.
出处
《中国临床研究》
CAS
2017年第6期835-837,共3页
Chinese Journal of Clinical Research
关键词
肺癌
淋巴结转移
多层螺旋CT
三维重建
轴位成像
肿瘤血管密度
病理学检查
Lung cancer
Lymph node metastasis
Multi-slice spiral computed tomography
Three-dimensionreconstruction
Axial imaging
Tumor vascular density
Pathological examination
