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老年牙周病患者感染病原菌的相关因素分析及其抗菌药物的应用效果 被引量:4

Analysis of Related Factors of Pathogens in Elderly Patients with Periodontal Disease and the Effect of Antimicrobial Agents
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摘要 目的探讨老年牙周病患者感染病原菌的相关因素及其抗菌药物的应用效果。方法在医院2015年10月—2016年9月期间诊治的老年牙周病患者中抽取50例作观察组,同期选取50名老年健康体检者作为对照组,对比两组受检者一般资料,分析老年牙周病患者感染病原菌的相关因素,并根据感染病原菌分布予以抗菌药物治疗,评估其抗菌药物应用效果。结果 (1)观察组、对照组在每日早晚刷牙、吸烟、刷牙时间超过3 min、合并两种以上基础性疾病、学历在高中及以上、常伴负性情绪、口腔卫生差项目上的比较,差异有统计学意义(P<0.01)。(2)本组50例牙周病患者共分离出100株病原菌,其中伴放线放线菌44株,占44.0%;牙龈卟啉单胞菌35株,占35.0%;生痰二氧化碳嗜纤维菌18株,占18.0%;其余病原菌3株,占3.0%。(3)奥硝唑组患者病原菌清除率是96.0%,高于甲硝唑组的76.0%(P<0.05)。结论老年牙周病患者感染病原菌的相关因素包括刷牙习惯差、刷牙时间短、吸烟、学历低、常伴负性情绪、口腔卫生差等,经奥硝唑治疗后临床效果肯定,可推广。 Objective To investigate the factors related to the infection of pathogens in elderly patients with perio- dontal disease and the effect of antibiotics. Methods Fifty elderly patients with periodontal disease diagnosed during the pe- riod from October 2015 to September 2016 were enrolled in the study group. Fifty elderly healthy subjects were selected as the control group. In the same way, data, analysis of elderly patients with periodontal disease infection pathogens related factors, and according to the distribution of infectious pathogens to be antimicrobial treatment, to assess the application of antimicrobi- al drugs. Results (1) Observation group, the control group in the morning and evening brushing teeth, smoking, brushing time more than 3rain, combined with two or more basic diseases, education in high school and above, often accompanied by negative emotions, oral hygiene difference between the statistics are statistically ( P 〈 0. 01 ) ; (2) 50 strains of periodontal dis- ease in this group were isolated from 100 strains of pathogens, of which 44 strains of actinomycetes, accounting for 44. 0% ; 35 cases of Porphyromonas gingivalus, accounting for 35.0%. (3) The eradication rate of pathogens in the ornidazole group was 96.0% , which was higher than that in the metronidazole group 76.0% ( P 〈 0. 05 ). Conclusion Aged periodontal dis- ease in patients with pathogens related factors include poor brushing habits, brushing time is short, smoking, low academic qualifications, often accompanied by negative emotions, poor oral hygiene, the treatment of ornidazole after the clinical effect of certain, can be promoted.
作者 金福 刘建明
出处 《现代医院》 2017年第6期900-902,共3页 Modern Hospitals
关键词 老年人 牙周病 感染病原菌 相关因素 抗菌药物 奥硝唑 Elderly People Periodontal Disease Pathogenic Bacteria Related Factors Antibiotics Oruidazole
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