超声心动图评价新生儿动脉导管闭合前后肺动脉压力的变化被引量：8

Echocardiographic evaluation of the changes of neonatal pulmonary arterial pressure before and after ductus arteriosus closure

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摘要目的应用超声心动图评价新生儿动脉导管闭合前后肺动脉压力的变化。方法选取经超声心动图确诊存在动脉导管未闭的新生儿41例,应用三尖瓣反流法评估其肺动脉收缩压,于服用布洛芬混悬液治疗3~7 d后复查超声心动图,观察动脉导管是否闭合,以及肺动脉收缩压、右房室腔大小、肺动脉主干内径的变化,分析肺动脉压力与动脉导管内径的相关性。结果 41例动脉导管未闭患儿,30例于治疗3 d后闭合,6例于治疗7 d后闭合,2例未闭合,3例死亡。36例经治疗后动脉导管闭合的新生儿,其动脉导管闭合后肺动脉收缩压较治疗前明显下降,右房室腔大小和肺动脉主干内径较治疗前明显缩小,差异均有统计学意义(均P<0.05)。41例患儿肺动脉压力与动脉导管内径呈正相关(r=0.77,P<0.01)。结论超声心动图在评价新生儿动脉导管闭合前后肺动脉压力的变化情况方面具有重要作用。 Objective To explore the changes of neonatal pulmonary arterial pressure before and after ductus arteriosus closure. Methods Forty-one cases of newborns with patent ductus arteriosus confirmed by echocardiography were collected.Tricuspid regurgitation methods were used to assess pulmonary artery systolic pressure. After 3 ~7 d treatment of ibuprofen suspension liquid,echocardiography were reexamined to observe whether ductus arteriosus was closed,and to observe the changes in the pulmonary artery systolic pressure,the right atrioventricular cavity size and the pulmonary artery trunk diameter. Correlation between pulmonary artery pressure and ductus arteriosus diameter were also analyzed. Results Forty-one cases of neonatal with patent ductus arteriosus were detected. Among them,3 cases died,30 cases ductus arteriosus closed after 3 d treatment,6 cases ductus arteriosus closed after 7 d,and 2 cases ductus arteriosus were remained open. After treatment,the pulmonary artery systolic pressure of 36 cases of patent ductus arteriosus significantly decreased than that before treatment,the size of right atrioventricular cavity and the diameter of pulmonary artery trunk significantly decreased than before treatment,the differences were statistically significant（all P〈0.05）. Pulmonary artery pressure of 41 newborns with patent ductus arteriosus was positively correlated with the diameter of the ductus arteriosus（r=0.77,P〈0.01）. Conclusion Echocardiography in evaluating the change of neonatal pulmonary arterial pressure before and after ductus arteriosus closure has a unique advantage.

作者亢春苗赵恩法牛华周英华黄丽丽刘保民

机构地区陕西省人民医院超声科西安交通大学第二附属医院超声研究室西电集团医院超声科西安高新医院超声科

出处《临床超声医学杂志》 2017年第4期269-271,共3页 Journal of Clinical Ultrasound in Medicine

关键词超声心动描记术新生儿动脉导管肺动脉压力 Echocardiography Neonate Ductus arteriosus Pulmonary arterial pressure

分类号 R540.45 [医药卫生—心血管疾病]

作者简介通信作者：刘保民，Email：dr．liubm@163．com

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参考文献2

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2杨春燕,卢宪梅,李文,赵翠芬,许平.超声心动图对评价新生儿窒息时缺氧性肺动脉高压左心功能减低的意义[J].中国小儿急救医学,2012,19(6):617-619. 被引量：5

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