摘要
以多乐氟为研究对象,进行了紫外分光光度法测定多乐氟中氟化钠含量的方法学研究,并以纯化水为溶出介质,测定了多乐氟48h的体外释放。结果显示,氟化钠在8.896μg^62.272μg有良好的线性,R2=0.997。48h的累积释放量为6.57%。
The research object is Duraphat. We studied on UV spectrophoto-metry to deter-mine the content of sodium fluorid in the methodology research. We also used the purifi-ed water as the dissolution medium, deter- mined the in vitro release of Duraphat in 48 hours. The results showed that sodium fluoride has a good linear in 8. 896μg -62. 272μg,R2 =0. 997. The cumulative release of 48 hours was 6.57%.
作者
舒泉湧
麻纪斌
邢建峰
翟帆
李宗霖
郭晨
SHU Quan-yong MA Ji-bin XING Jian-feng ZHAI Fan LI Zong-lin GUO Chen(Xi＇an Jiaotong University, Xi＇an 710061, Shaanxi, China Shaanxi institute of traditional Chinese medicine, Xianyang 712000, Shaanxi, China Shaanxi Pharmaceutical Development Center, Xi＇an 710075, Shaanxi, China)
出处
《合成材料老化与应用》
2017年第2期79-81,共3页
Synthetic Materials Aging and Application
关键词
多乐氟
紫外分光光度法
含量测定
释放度
duraphat, UV spectrophotometry, determination of content, dissolution rate
作者简介
通讯作者：邢建峰，博士，教授，硕士生导师，研究方向为新型给药系统的设计与研究以及消化系统疾病治疗药物的研究；E-mail：xajdxjf@mail．xjtu．edu．cn；Tel：15829081518
