摘要
目的探讨γ-谷氨酰转移酶（gamma-glutamyltransferase，GGT）与飞行员冠心病危险因素的相关性。方法纳入2015年3月至12月于空军总医院进行改装新机体检的飞行员138例，均为男性。根据GGT四分位数分为4组：A组（GGT〈13U／L，31人），B组（13U／L≤GGT〈16U／L，32人），C组（16U／L≤GGT〈25U／L，40人），D组（GGT≥25U／L，35人）。记录受检者年龄、飞行时间、飞行机种、吸烟、饮酒、家族史、高血压、糖尿病病史等资料；测量身高、体重及血压；抽取静脉血，监测FPG、TG、TC、HDL-C、LDL-C、GGT、尿酸（uricacid，UA）、肝肾功能等。结果4组飞行员年龄、BMI、TG、TC、LDL-C、UA差异均有统计学意义（F=4．638～9．315，P〈0．01）。其中c组TC、LDL-C、UA高于A组（t=2．819～3．309，P〈0．01）；D组年龄、BMI、TG均高于A、B、c组（T=2．216～4．350，P〈0．05），TC、LDL-C均高于A、B组（t=2．196～3．553，P〈0．05），UA高于A组（T=3．949，P〈0．05）。改装体检飞行员GGT水平与BMI、TG、TC、LDL-C、UA之间存在线性相关（r=0．320-0．394，P〈0．01）。结论GGT可能是影响飞行员冠心病危险因素的因子，应重视GGT的监测作用。
Objective To investigate the correlation between gamma-glutamytransferase （GGT） and risk factors of coronary heart disease （CHD） in the military pilots. Methods Totally 138 male pilots who were examined in Air Force General Hospital for transition from March 2015 to December 2015 were selected. All pilots were divided into 4 groups depending on the levels of GGT： group A （GGT〈13 U/L, n=31）, group B （13 U/L≤GGT〈16 U/L, n=32）, group C （16 U/L≤GGT〈25 U/L, n=40） and group D （GGT≥25 U/L, n=35）. Age, flying hours, type of aircraft, smoking history, drinking history, family history, history of hyhertension and diabetes were investigated and recorded. Blood pressure, height, weight and body mass index （BMI） were measured. FPG, TG, TC, HDL-C, LDL-C, uric acid （UA）, GGT, liver function and kidney function were monitored. Results There were significant difference on age, BMI and the levels of TG, TC, LDL-C, UA among 4 groups （F=4. 638-9. 315, P〈0. 01）. The levels of TC, LDL-C, UA of group C were significant higher than that of group A （t=2. 819-3. 309, P〈0.01）. The levels of age, BMI, TG of group D were significant higher than that of group A, B and C （t=2. 216-4. 350, P〈0.05）. The levels of TC and LDL-C of group D were significantly higher than that of group A and B （t=2. 196- 3. 553, P〈0.05）, and the level of UA in group A was significantly higher than that of group A （t= 3. 949, P〈0.05）. The level of GGT was linearly correlated with BMI, TG, TC, LDL-C and UA （r=0. 320-0. 394, P%0.01）. Conclusions The levels of GGT may be the risk factor of CHD. If is suggested to pay more attention on the monitoring of it.
出处
《中华航空航天医学杂志》
CSCD
2016年第4期258-262,共5页
Chinese Journal of Aerospace Medicine
基金
全军后勤科研“十二五”重大项目
作者简介
田建伟，Email：tianjianwei029@aliyun．com
