摘要
目的探讨不同微创手术方式经鼻蝶治疗垂体瘤的效果。方法选取垂体瘤患者80例,根据手术方法不同将患者分为两组,其中38例行神经内镜下经鼻蝶垂体瘤切除术的患者为神经内镜组,42例行显微镜下经鼻蝶垂体瘤切除术的患者为显微镜组,观察两组患者的手术情况及术后并发症发生情况。结果神经内镜组患者的术中出血量为(45.09±10.31)ml,少于显微镜组的(77.82±12.06)ml,手术时间、住院时间分别为(121.44±27.63)min、(6.74±1.14)d,均短于显微镜组的(154.67±38.20)min、(10.25±1.47)d,差异均有统计学意义(P﹤0.05);神经内镜组患者的肿瘤全切比例为94.74%,高于显微镜组的71.43%(P﹤0.05);神经内镜组患者的术后并发症发生率为7.89%,低于显微镜组的26.19%(P﹤0.05)。结论神经内镜下经鼻蝶治疗垂体瘤安全有效,具有创伤小、术后并发症少等优点,建议可在临床上进一步推广应用。
Objective To investigate the effect of endoscopic or microscopic resection as different minimally inva-sive transsphenoidal surgeries in the treatment of pituitary adenoma. Method 80 cases of patients with pituitary adeno-ma were enrolled in the study, in which 38 cases were treated with endoscopic transsphenoidal pituitary adenoma resec-tion （endoscopic surgery group）, and the other 42 cases were administered with microscopic pituitary adenoma surgery （microscopic surgery group）, the operative measures and incidence of postoperative complications of the two groups were observed. Result The blood loss was （45.09±10.31） ml vs （77.82±12.06） ml in endoscopic surgery group and microscop-ic surgery group, respectively, and the operative time were （121.44±27.63） min vs （154.67±38.20） min, besides, the hospi-tal stay were （6.74 ± 1.14） d vs （10.25 ± 1.47） d in the two groups, with statistically significant differences observed （P〈0.05）;94.74%of patients had complete resection in endoscopic surgery group, while the proportion was 71.43%in the other （P〈0.05）;As for incidence of postoperative complications, it was 7.89%in endoscopic surgery group, which was significantly less than that of the microscopic surgery group at 26.19%（P〈0.05）. Conclusion Endoscopic transsphenoi-dal pituitary adenoma resection is a safe and effective surgery, with the advantages of minimal invasiveness as well as less postoperative complications.
作者
黄文辉
曾白云
肖仕印
HUANG Wenhui ZENG Baiyun XIAO Shiyin(Department of Neurological Surgery, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, Guangdong, China)
出处
《癌症进展》
2017年第2期159-161,共3页
Oncology Progress
关键词
神经内镜
显微镜
鼻蝶
垂体瘤
治疗效果
endoscopy
microscope
sphenoid
pituitary adenoma
therapeutic effect
作者简介
通信作者（correspondingauthor），邮箱：hwh136028@126．com
