期刊文献+

结肠癌肿瘤干细胞相关因子研究进展 被引量:7

原文传递
导出
摘要 结肠癌是最常见的消化道恶性肿瘤之一,在世界范围的肿瘤发病率排名前列,每年约超过100万新发病例,呈逐年增加趋势,近年来,随着人们生活方式和饮食结构的变化,其发病趋于年轻化。结肠癌的复发转移和药物抵抗是导致其病死率高和预后差的重要影响因素。研究结肠癌肿瘤干细胞特异性标志物,探索其相关信号通路,有利于阐明结肠癌发生发展机制,为结肠癌靶向治疗提供新的思路。
出处 《中国肿瘤临床与康复》 2017年第3期376-380,共5页 Chinese Journal of Clinical Oncology and Rehabilitation
关键词 结肠肿瘤 肿瘤干细胞 生物学标记物 Colon neoplasms Cancer stem cells Biological markers
作者简介 曲泽,女,硕士研究生,主要从事胃肠外科专业。 通信作者:侯明星,Email:hmx6412@163.com
  • 相关文献

参考文献10

二级参考文献149

  • 1庄建良,苏子剑,许荣誉.活化白细胞黏附分子及其与肿瘤侵袭转移的关系[J].国际病理科学与临床杂志,2006,26(6):479-482. 被引量:6
  • 2潘东亮,严秋哲,杨勇.KAI-1、Ki-67和HER-2/neu表达在T_(1-3)N_0M_0肾癌术后转移中的意义[J].中国癌症杂志,2007,17(3):248-251. 被引量:7
  • 3Giuliani F, De Vita F, Colucci G, et al. Maintenance therapy in colon cancer [J]. Cancer Treat Rev, 2010, 36 (3) :s42 -s45.
  • 4Yoshida A, Hsu LC, Dave' V. Retinal oxidation activity and biological role of human cytosolic aldehyde dehydrogenase [J]. Enzyme, 1992, 46 (4 -5) :239 -244.
  • 5Huang EH, Hynes MJ, Zhang T, et al. Aldehyde dehydro- genase 1 is a marker for normal and malignant human colonic stem cells ( SC ) and tracks SC overpopulation during colon tumorigenesis [J]. Cancer Res,2009, 69(8) :3382 - 3389.
  • 6Luo J, Zha S, Gage WR, et al. Alpha-methylacyl-CoA racemase : a new molecular marker for prostate cancer [ J ]. Cancer Res, 2002, 62 ( 8 ) :2220 - 2226.
  • 7Hess DA, Craft TP, Wirthlin L, et al. Widespread non- hematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity [ J ]. Stem Ceils, 2006, 26(8) :611 -620.
  • 8Chute JP, Muramoto GG, Whitesides J, et al. Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells [ J ]. Proc Natl Acad Sci USA,2006, 103 (31) :11707 - 11712.
  • 9Fallon P, Gentry T, Bailer AE, et al. Mobilized peripheral blood SSC loALDHbr cells have the phenotypic and functional properties of primitive haematopoietic cells and their number correlates with engraftment following autologous transplantation [J]. Sr J naematol, 2003, 122 (1): 99-108.
  • 10Li T, Su Y, Mei Y, et al. ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients outcome [ J ] . Laboratory Investigation, 2 010, 9 0 (2) : 234 -244.

共引文献40

同被引文献75

引证文献7

二级引证文献29

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部