摘要
目的探讨雌激素联合氧化再生纤维素防粘连膜在宫腔粘连治疗中的临床效果。方法收集2015年1月至2015年8月人院的80例宫腔粘连患者随机分为两组，对照组患者给予雌激素治疗，实验组患者则加施氧化再生纤维素防粘连膜干预，比较两组患者治疗前后月经量与子宫内膜厚度、宫腔粘连总体治疗效果、粘连复发率、药物不良反应与妊娠情况。结果实验组患者治疗后3个月月经量为（52．82±8．50），子宫内膜厚度为（8．59±0．34），显著高于对照组的（34．33±7．27）、（8．03±0．45），差异具有统计学意义（均P〈0．01）；实验组患者治疗总有效率（100．00％）明显高于对照组（87．50％），差异具有统计学意义（P〈0．05）；实验组患者粘连复发率（10．00％）明显低于对照组（31．43％），差异具有统计学意义（P〈0．05）；两组患者药物不良反应率（12．50％比7．50％）比较差异无统计学意义（P〉0．05）。结论雌激素联合氧化再生纤维素防粘连膜在宫腔粘连治疗中的临床效果显著，安全性较高，借鉴意义重大。
Objective To investigate the clinical effect of estrogen combined with oxidized regenerated cellulose anti-adhesion film for intrauterine adhesions. Methods 80 patients with intrauterine adhesions treated at our hospital from January to August, 2015 were randomly divided into a control group and an experimental group. The control group were treated with estrogen; in addition, the experimental group were intervened with oxidized regenerated cellulose anti-adhesion film. The menstrual volume, endometrial thickness, overall treatment effect, adhesions relapse rate, adverse drug reactions, and pregnant conditions were compared between these two groups before and after treatment. Results The menstrual volume and endometrial thickness were （52.82 ＋ 8.50） and （8.59 ~ 0.34） in the experimental group and were （34.33 ±7.27） and （8.03±0.45） in the control group 3 months after treatment, with statistical differences （P 〈 0.01）. The total effective rate was significantly higher and adhesions relapse rate was significantly lower in the experimental group than in the control group （100% vs. 87.5% and 10.00% vs. 31.43%）, with statistical differences （P 〈 0.05） 0. There was no statistical difference in the incidence of adverse drug reactions between these two groups （2.5% vs. 7.5%, P 〉 0.05）. Conclusion Estrogen combined with oxidized regenerated cellulose anti-adhesion film for intrauterine adhesions is effective and safe and of great significance.
出处
《国际医药卫生导报》
2017年第3期341-344,共4页
International Medicine and Health Guidance News
关键词
宫腔粘连
雌激素
氧化再生纤维素防粘连膜
复发
药物不良反应
Intrauterine adhesions
Estrogen
Oxidized regenerated cellulose anti-adhesion film
Relapse
Adverse drug reactions
