摘要
目的:观察固肾安胎方联合常规西药治疗肾脾两虚型复发性流产临床观察及相关免疫性。方法:采用回顾性分析随机选取2013年2月~2015年12月本院收治复发性流产(RSA)患者再次妊娠者60例,根据随机分组法分为两组,A组为研究组,采用固肾安胎方联合常规西药治疗方案;B组为参照组,采用常规西药治疗方案。结果:A、B两组患者自然流产次数对比,差异无意义(P=0.874)。A、B两组患者初诊时孕周对比,差异无意义(P=0.516)。A、B两组患者初诊时中医症状积分分别为(1.35±4.98)和(11.86±3.72),且A、B两组患者初诊时病情分级对比,差异无意义(P=0.264)。A、B两组患者治疗前血清(B-HCG)和孕酮水平的对比,差异无意义(P=0.617)。A组有1例患者胞胎失败,29例治愈,总有效率为96.7%。B组10例治疗无效,20例治愈,总有效率为66.7%。A、B两组患者治疗后妊娠结局的对比,差异有意义(P=0.026)。A组治愈8例,显效12例,有效7例,无效3例,总有效率为90.0%。B组治愈4例,显效6例,有效10例,无效10例,总有效率为66.7%。A、B两组治疗后中医症状改善情况对比,差异有意义(P=0.042)。A、B两组患者流产次数与好娘结局关系的对比,经过Fisher确切概率法分析,差异有意义(P=0.032)。A、B两组患者治疗后血清对比,差异无意义(P>0.05)。A、B两组患者治疗后的6和8周末孕酮对比,差异有意义(P<0.05);A、B两组患者治疗后的10周末孕酮对比,差异无意义(P>0.05)。结论:固肾安胎方联合常规西药治疗肾脾两虚型复发性流产效果显著,值得推广。
Objective： To investigate the effect of using Gushen Antai Recipe combined with routine western medicine in the treatment of kidney and spleen deficiency type recurrent spontaneous abortion and study on relevant immunity. Methods： A retrospective analysis of randomly selected from February 2013 to December 2015 admitted to our hospital with recurrent spontaneous abortion（ RSA） was pregnant again in 60 cases,according to random number table method were divided into two groups,A group was the study group,the use of Gushen Antai Recipe combined with conventional western medicine treatment; B group was the reference group,conventional western medicine treatment. Results： The number of spontaneous abortion between the two groups of patients was insignificant difference（ P = 0. 874）. A,B groups of patients with newly diagnosed gestational age when compared was insignificant difference（ P = 0. 516）. Newly diagnosed TCM symptom scores of the A,B groups respectively were（ 1. 35 ±4. 98） and（ 11. 86±3. 72）,and disease classification of the A,B groups of patients with newly diagnosed was insignificant difference（ P = 0. 264）. Serum（ B-HCG） and progesterone levels of the A,B groups of patients before treatment was insignificant difference（ P = 0. 617）. 1patients of the A group fail births,29 cases were cured,the total effective rate was 96. 7%. 10 cases of group B were effect,20 cases were cured,the total effective rate was 66. 7%. Comparing A,B groups of patients after pregnancy outcomes was significant difference（ P = 0. 026）. 8patients of the A group were cured,12 cases were markedly effective,7cases were effective,3cases were ineffective,the total effective rate was 90. 0%. Four cases of the group B were cured,6cases were markedly effective,10 cases were effective,10 cases were ineffective,the total effective rate was 66. 7%. After the A,B treatment,the clinical symptoms improvement compared between the two groups were significant difference（ P = 0. 042）. Comparative A,B groups of the number of abortions and a good relationship between the outcome of the mother was significant（ P = 0. 032） after Fisher exact test analysis. Serum contrast of A,B groups after treatment was insignificant difference（ P〈0. 05）. Progesterone contrast in 6,8weekend of A,B groups after treatment,the difference was significant（ P〈0. 05）; 10 weekend progesterone Contrast of the A,B groups after treatment,the difference was insignificant（ P〈0. 05）. Conclusion： Gushen Antai Recipe combined with routine western medicine for kidney and spleen deficiency type recurrent spontaneous abortion is significantly effective,it is worth promoting.
出处
《四川中医》
2017年第1期115-118,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
湖南省医药卫生科研计划课题项目(编号:C2013-053)
关键词
固肾安胎
复发性流产
中西结合
肾脾两虚
Gushen tocolysis
Recurrent abortion
Combination of traditional Chinese and western medicine
Spleen and kidney deficiency
