摘要
目的:分析并比较阿替普酶和尿激酶溶栓治疗急性ST段抬高型心肌梗死的临床效果。方法:选择2013年3月至2016年6月在我院收治的90例急性ST段抬高型心肌梗死作为研究对象,随机分为观察组和对照组(各45例)。对照组采用尿激酶治疗,观察组采用阿替普酶治疗,比较两组患者的治疗效果。结果:观察组冠状动脉再通率明显高于对照组,两组每个时间段之间比较,差异明显(P<0.05);2周内两组脑出血、消化道出血及临床不良事件总发生率之间比较,观察组均明显低于对照组(P<0.05)。结论:对于急性ST段抬高型心肌梗死患者,采用溶栓治疗时,阿替普酶具有更高的治疗价值,临床治疗的安全性更高,值得在临床上推广使用。
Objective：To analyze and compare the clinical effect of alteplase and urokinase thrombolysis on acute ST segment elevation myocardial infarction.Methods：Ninety patients with acute ST-segment elevation myocardial infarction admitted to our hospital from March 2013 to June 2016 were randomly divided into observation group（n=45）and control group（n=45）.The control group was treated with urokinase,and the observation group was treated with alteplase.The therapeutic effect of the two groups was compared.Results：The recanalization rate of coronary artery in the observation group was significantly higher than that in the control group（P〈0.05）.There was significant difference between the two groups in cerebral hemorrhage,gastrointestinal bleeding and clinical adverse events（P〈0.05）.Conclusion：For patients with acute ST-segment elevation myocardial infarction,the use of thrombolytic therapy,alteplase has a higher therapeutic value,the clinical treatment of higher safety,worthy of clinical use.
出处
《四川生理科学杂志》
2016年第4期226-227,共2页
Sichuan Journal of Physiological Sciences
关键词
阿替普酶
尿激酶
溶栓
急性ST段抬高型心肌梗死
Alteplase
Urokinase
Thrombolysis
Acute ST segment elevation myocardial infarction
作者简介
李军，男，主治医师，主要从事心内科临床诊治工作，Email：q1980917@163．com。
