摘要
目的慢性扁桃体炎(CT)和腺样体肥大(AH)是引起阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的最常见原因。本研究探讨扁桃体和(或)腺样体切除后外周血平均血小板体积(MPV)变化及其意义。方法 40例被诊断为腺样体肥大和(或)慢性扁桃体炎患儿全麻下行腺样体和(或)扁桃体切除术,设为手术组,年龄4到16岁。38例4到16健康岁儿童设为对照组。分别检测外周血平均血小板体积(MPV),血小板计数(PLT),白细胞计数(WBC)和血红蛋白(HB)水平。结果手术组MPV水平明显低于对照组(P<0.001),手术组PLT明显高于对照组(P<0.001);手术组WBC和HB水平与对照组相比无统计学意义。结论4到16岁儿童由慢性扁桃体炎(CT)和腺样体肥大(AH)引起的阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与外周血低水平血小板平均体积(MPV)有关。
Objective Chronic tonsillitis（CT）and adenoid hypertrophy（AH）is the most common cause of obstructive sleep apnea hyponea syndrome（OSAHS）.In the present study,we evaluated the relationship between mean platelet volume（MPV）and CT and AH which is the most frequent cause leading OSA in children.Methods A total of40 children aged between 4and 16,who underwent adenoidectomy or adenotonsillectomy with a diagnosis of AH and/or CT were recruited as operation group.38 healthy controls aged between 4and 16 were employed as control group.Mean platelet volume（MPV）values,platelet count（PLT）,white blood cell count（WBC）and hemoglobin（Hb）levels were recorded individually.Results It was found that MPV values in operation group were significantly lower than control group（P〈0.001）,whereas PLT in operation group was significantly higher than control group（P〈0.001）.There were no significant differences in WBC and HB values among groups.Conclusion OSAHS caused by CT-AH is associated with low MPV values in childhood aged 4to 16.
作者
郑海明
ZHENG Hai-ming.(Department of Otolaryngological , Traditional Chinese Medicine Hospital of Baoji City ,Baoji 721001 ,China)
出处
《中国实验诊断学》
2016年第11期1872-1874,共3页
Chinese Journal of Laboratory Diagnosis
