摘要
三阴性乳腺癌(TNBC)具有特殊的生物学行为及临床病理学特征,侵袭性强,恶性程度高,临床缺乏有效的治疗方法,预后较差。TNBC较非TNBC型乳腺癌在MRI上具有一定的特征表现。灌注加权成像、扩散加权成像及磁共振波谱成像等功能MRI技术运用多定量参数指标可以定量评估TNBC血流灌注情况及细胞代谢状态,并对TNBC术前新辅助化疗效果具有监测作用。就MRI对TNBC与非TNBC的鉴别诊断及TNBC新辅助化疗评估及预后检测予以综述。
Triple-negative breast cancer（TNBC） is characterized by distinct biological and clinical pathological features.Due to its high aggressive and malignant, and lack of effective therapeutic targets, it has a worse prognosis.Compared with Non-TNBC, TNBC shows some characteristics in magnetic resonance imaging. Functional MR imaging, such as perfusion weighted imaging,diffusion-weighted imaging, and magnetic resonance spectroscopy, can quantitatively evaluate the tumor microvascular perfusion and cellular metabolism, and can also monitor neoadjuvant chemotherapy effect on TNBC.Here, we summarized the MRI application status on identifying of TNBC and assessing of neoadjuvant chemotherapy efficacy.
出处
《国际医学放射学杂志》
2016年第6期633-636,670,共5页
International Journal of Medical Radiology
关键词
三阴性乳腺癌
功能磁共振成像
血流灌注
定量参数
新辅助化疗
Triple-negative breast cancer
Functional magnetic resonance imaging
Blood perfusion
Quantitative parameter
Neoadjuvant chemotherapy
作者简介
通讯作者：汤光宇．E-mail：tgy17@126．com.审校者
