摘要
目的对比观察36条简明健康状况调查表(SF-36)与明尼苏达州心力衰竭生活质量问卷(MLHFQ)在慢型克山病患者生活质量评价中的作用。方法依据《克山病诊断》(WS/T 210-2011)标准,选择符合入选条件的慢型克山病患者146例,采用中文版SF-36及MLHFQ分别对受检者HRQOL进行问卷调查,并应用相关分析、多元线性回归对两个问卷评分的相关性及患者HRQOL的影响因素进行分析探讨。结果 (1)相关分析显示,MLHFQ得分与SF-36总分、心理健康内容、生理健康内容的得分呈高度负相关(r=-0.776、-0.750、-0.733,P均<0.01))。(2)不同NYHA心功能级别的慢型克山病患者HRQOL相比较,MLHFQ和SF-36在心功能Ⅲ级与心功能Ⅱ级的患者间相比较有统计学意义(P<0.01),在Ⅳ级与Ⅲ级间相比较无差异(P>0.05)。(3)多元逐步回归分析显示,影响慢型克山病患者MLHFQ总分及SF-36总分的主要因素为NYHA心功能分级、病程,对MLHFQ总分及其各领域得分、SF-36总分及其不同方面得分均有影响的因素为NYHA心功能分级。结论 (1)慢型克山病患者SF-36与MLHFQ的得分具有良好的相关性。(2)SF-36及MLHFQ在区别慢性克山病患者中具有轻度心力衰竭患者的生存质量方面具有重要的作用。(3)NYHA心功能分级和病程是影响慢型克山病患者生存质量的重要因素。(4)SF-36用于慢型克山病患者生存质量的评价具有重要的参考价值。
Objective To compare the effects of 36-item short-form health survey（SF-36） and Minnesota living with heart failur questionnaire（MLHFQ） for assessment of health-related quality of life（HRQOL） in patients with chronic Keshan disease in China. Methods According to the Diagnosis of Keshan disease WS/T210-2011 146 patients with chronic Keshan disease were se- lected. The HRQOL was assessed in those patients by using the Chinese version of SF-36 and MLHFQ. Correlation analysis and multiple linear regression were used to analyse the correlation and the influence factors of HRQOL. Results （1） From the results of correlation analysis, MLHFQ scores was significantly negatively correlated with SF-36 total scores, content of mental health and physical health. （2） There was significant difference between SF-36 and MLHFQ scores in NYHA cardiac function classifica- tion II and III （ P 〈0.01）. （3）There was no significant difference between SF-36 and MLHFQ scores in NYHA cardiac function classification IV and IIl. The multivariate linear regression analysis indicated that the influencing factors of SF-36 and MLHFQ total scores were NYHA cardiac function classification, course of disease. NYHA cardiac function classification have effects on the MLHFQ total score and its field score, SF-36 total score and the score of different aspects of the factors. Conclusion （1） SF-36 scores have obvious correlation with MLHFQ in patients with chronic Keshan. （2） SF-36 and MLHFQ play important roles in dis- tinguishing different mild heart failure in patients with chronic keshan disease. （3） NYHA functional class and course of disease were relatively dominant predictors of patients HRQOL among all variables. （4） SF-36 has important reference value for quality of llfe evaluation in Chinese patients with chronic Kesban disease
出处
《中国地方病防治》
CAS
北大核心
2016年第8期845-847,共3页
Chinese Journal of Control of Endemic Diseases
基金
山东省医药卫生科技发展计划项目(2015WS0288)
作者简介
通信作者：王园园（1981-），女，硕士，主治医师，从事地方病防治防治工作，Email：ttchenxing@163．com
