摘要
目的研究嗜酸性粒细胞增多症的病因,为临床提供科学依据。方法选取在2015年2月—2016年2月期间该院收治的156例嗜酸性粒细胞增多症患者作为研究对象,随机分成试验组和对照组,每组78例。对照组患者给予嗜酸性粒细胞症常用药物强的松治疗,试验组在给予强的松治疗的基础上,根据患者不同情况加减药物治疗,并采用调查问卷的方法对患者疾病类型、病因等等进行调查。结果调查的两组患者经不同用药方案治疗后,试验组患者治愈41例,治愈率为52.56%,情况有所改善患者33例,起效率为42.31%,总有效率为94.87%;对照组患者治愈21例,治愈率为26.92%,情况有所改善的患者31例,起效率为39.74%,总有效率为66.67%。经统计学分析,试验组总有效率明显高于对照组,差异有统计学意义(P<0.01);试验组患者嗜酸性粒细胞轻度增多者37例,中度增多者39例,严重增多症2例;对照组中患者轻度增多者36例,中度增多者41例,严重增多者1例;引起嗜酸性粒细胞增多的原因主要有寄生虫、支气管哮喘、血管神经性水肿、药物过敏、念珠菌感染、淋巴干酪样结核病、湿疹、慢性粒细胞白血病、类风湿性关节炎及恶性肿瘤等。结论通过对患者病因分析,并根据症状采取不同药物治疗,有助于改善患者嗜酸性粒细胞增多情况,临床疗效明显,值得临床推广。
Objective To research the causes of hypereosinophilic syndrome and provide scientific basis for the clinic.Methods 156 cases of patients with hypereosinophilic syndrome admitted and treated in our hospital from February 2015 to February 2016 were selected as the research objects and randomly divided into two groups with 78 cases in each, the control group adopted the common drug prednisone treatment of hypereosinophilic syndrome, while the test group adopted the modified drug treatment according to different conditions of patients on the basis of the control group, and the disease type and cause were surveyed by the questionnaire. Results After treatment, in the test group, 41 cases were cured, and the cure rate was 52.56%, 33 cases were improved, and the effective rate was 42.31%, and the total effective rate was 94.87%, in the control group, 21 cases were cured, and the cure rate was 26.92%, 31 cases were improved, and the effective rate was39.74% and the total effective rate was 66.67%, and the statistical analysis showed that the total effective rate in the test group was obviously higher than that in the control group, and the difference was obvious with statistical significance（P〈0.01）, and in the test group, there were 37 cases with mild increase of eosinophils, 39 cases with moderate increase of eosinophils and 2 cases with severe increase of eosinophils, in the control group, there were 36 cases with mild increase of eosinophils, 41 cases with moderate increase of eosinophils and 1 cases with severe increase of eosinophils, and the main causes of hypereosinophilic syndrome were parasite, bronchial asthma, angioneurotic edema, drug allergy, candidosis, lymph caseous tuberculosis, eczema, chronic granulocytic leukemia, arthritis pauperum and malignant tumor. Conclusion The symptomatic treatment and adopting the treatment of different drugs according to symptoms contribute to improving the hypereosinophilic syndrome of patients and eliminating the disease sufferings, and the clinical curative effect is obvious, which is worth clinical promotion.
出处
《中国卫生产业》
2016年第30期175-177,共3页
China Health Industry
作者简介
肖中平（1963.12-）,男,吉林长春人,硕士,主任医师,研究方向：血液肿瘤临床治疗.
