摘要
糖尿病属中医的"消渴症",是一种病因复杂、无根治手段且并发症多、致残率和病死率都较高的慢性疾病。中药治疗消渴症讲究标本兼治,不少处方含有动物源药物或单方动物药;动物源类药物具有活血祛瘀等独特功效和治疗作用。本文从现有治疗糖尿病的药物出发,对中药复方中治疗消渴证的单味动物源类药物按照作用机制进行总结与分析,以期为开发新型动物源类治疗糖尿病药物提供借鉴。
Diabetes,so-called“emaciation-thirst disease”in traditional Chinese medicine(TCM),is a prevalent chronic dis-ease with complicated etiology,incurable and multiple complications,as well as extremely high morbidity and mortality. TCM pays at-tention to tackling the problem in the treatment of emaciation-thirst disease,and many prescriptions are single animal medicine or con-tain animal-original drug;animal-original drugs possess stasis and other unique characteristics and therapeutic effects. Based on the current anti-diabetic drugs,the review gives an in-depth summary and analysis on the single animal-original drugs derived from the complexes of TCM in the treatment of diabetes according to their mechanism of action,with the aim to provide reference for developing new animal-original drugs to treat diabetes.
出处
《国际药学研究杂志》
CAS
CSCD
北大核心
2016年第5期849-857,共9页
Journal of International Pharmaceutical Research
基金
国家自然科学基金资助项目(81360679)
云南省高新技术产业发展项目(云发改高技[2012]1956号)
云南省战略性新兴产业发展专项资金项目(云发改高技[2013]1527号)
2011省级协同创新中心“中国西南药用昆虫记蛛形类资源开发利用协同创新中心”建设项目(云教科[2012]25号)
作者简介
杨红,女,在读硕士研究生,研究方向:昆虫动物药物开发标准制定,Tel:0872-2257401,E-mail:hongdaoyouli1989@163.com
通讯作者:巫秀美,女,博士,硕士生导师,研究方向:昆虫生物医药研发,Tel:0872—2257401,E-mail:wxm6865@163.com