摘要
目的:探讨临床药师在非小细胞肺癌(NSCLC)患者治疗中药学监护的效果。方法:试验组中临床药师通过参与试验组患者化疗方案制定、护士给药指导、对患者用药后的疗效和不良反应进行跟踪监护,对照组无药师参与。比较试验组和对照组患者的不良反应发生情况。结果:试验组患者明显减少化疗辅助用药,不良反应发生率显著减少,恶心、呕吐(P<0.001)、骨髓抑制(P=0.002)和肝功能损伤(P=0.014)与对照组相比减少,具有统计学差异。结论:临床药师对NSCLC治疗的药学干预措施有效可行,促进临床化疗方案有效执行,提高了化疗效果和改善了患者生活质量。
Objective： To investigate the mode and effects of pharmaceutical care for non -small cell lung cancer （ NSCLC） with clinical pharmacists＇ participation. Methods： Clinical pharmacists participated in planning chemotherapy, guiding nurse administration, tracking efficacy and dealing with adverse reactions. Then, the adverse reactions of test group and control group were analyzed comparatively. Results： Clinical pharmacists＇ intervention significantly reduced the use of adjuvant drugs and the incidence of adverse drug reactions including nausea and vomiting （ P〈0.001）, myelosuppression （ P=0.002） and liver injury （ P=0.014）. Conclusion： The clinical pharmacists＇ involvement in the treatment of NSCLC is feasible and effective, promoting the effective implementation of clinical chemotherapy and improving the effect of treatment and the quality of life in NSCLC patients.
出处
《药学与临床研究》
2016年第5期413-416,共4页
Pharmaceutical and Clinical Research
基金
江苏省药学会药学科研项目(201311)
关键词
非小细胞肺癌
化疗
临床药师
药学监护
Non-small cell lung cancer
Chemotherapy
Clinical pharmacists
Pharmaceutical care
作者简介
通讯作者张晋萍,女,副主任药师E-mail：zjp16500@163.com
