摘要
The toxic effects of lead on normal rat kidney epithelial cells（NRK cells）may occur via various pathways.However,the role of intrinsic mitochondrial pathway in Lead-induced apoptosis in NRK cells has not been investigated.The purpose of our study was to investigate cytotoxic responses and cell apoptosis mediated by lead in NRK cells.
The toxic effects of lead on normal rat kidney epithelial cells（NRK cells）may occur via various pathways.However,the role of intrinsic mitochondrial pathway in Lead-induced apoptosis in NRK cells has not been investigated.The purpose of our study was to investigate cytotoxic responses and cell apoptosis mediated by lead in NRK cells.
基金
supported by program for science and technology development of Henan province(132102110036)
作者简介
These authors contributed equally to this work. Biographical notes for the tirst authors： HE Xiu Yuan, born in 1964, female, PhD, Associate Professor, majoring in animal nutrition metabolic disease and poisoning diseaseThese authors contributed equally to this work. Biographical notes for the tirst authors： YUAN Li Yun, born in 1979, female, PhD, instructor, majoring in animal toxicology researchThese authors contributed equally to this work. Biographical notes for the tirst authors： LI Yong Tao, born in 1986, male, PhD, instructor, majoring in immune prevention and control of animal infectious diseases.
