摘要
目的通过血流变学指标临床观察饮食干预结合硫酸镁静脉给药治疗妊娠高血压综合征的临床疗效情况。方法电脑抽签将本院2014年12月-2015年12月收治的妊娠高血压综合征患者110例随机分成观察组、对照组各55例,对照组仅给予硫酸镁静脉给药治疗,观察组在对照组基础上结合饮食干预,对两组患者的血流变学指标变化情况进行回顾性比较分析。结果经治疗,观察组在全血黏度（高切、中切、低切）、血浆黏度、红细胞聚集指数方面均显著优于对照组各项指标,有统计学意义（P〈0.05）;观察组在凝血酶时间、凝血原时间、活化部分凝血活酶时间、纤维蛋白原方面均显著优于对照组各项指标,有统计学意义（P〈0.05）。结论经饮食干预结合硫酸镁静脉给药治疗妊娠高血压综合征患者后,患者血流变学指标及凝血指标改善显著,值得临床应用推广。
Objective To observe the clinical efficacy of treatment of pregnancy-induced hypertension using dietary intervention combined with intravenous magnesium sulfate by index of blood rheology. Methods 110 patients with pregnancy induced hypertension were selected randomly by computer ballot from December 2014 to December 2015 in our hospital. The patients were divided into observation group and control group, 55 cases in each. Patients in control group were received intravenous magnesium sulfate treatment, and patients in control group were received intravenous magnesium sulfate combined with dietary intervention treatment. Blood rheology index changes in the two groups were analyzed retrospectively comparatively. Results After treatment, the indexes of whole blood viscosity（high shear, shear, low shear）, plasma viscosity, erythrocyte aggregation index of observation group were significantly better than the control group, P〈0.05, with statistical significance. And the indexes of thrombin time, prothrombin time, activated part thromboplastin time, fibrin principles of observation group were significantly better than the control group, P〈0.05, with statistical significance. Conclusion The blood rheology indexes and blood coagulation indexes of the patients were improved significantly by the treatment of Pregnancy-induced hypertension using dietary intervention combined with intravenous magnesium sulfate, which was worthy of clinical application.
出处
《中国医药科学》
2016年第10期77-79,共3页
China Medicine And Pharmacy
关键词
饮食干预
硫酸镁
妊娠高血压综合征
血流变学
Dietary intervention
Magnesium sulfate
Pregnancy-induced hypertension
Blood rheology
