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基于体素内不相干运动的扩散加权成像在肿瘤诊断中的研究进展 被引量:13

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摘要 DWI可检测活体组织细胞内外水分子扩散运动的变化,其ADC已用于人体肿瘤的诊断及鉴别诊断。随着对DWI理论研究的不断深入,学者们认为传统的DWI序列ADC值计算模型具有一定局限性。首先,人体组织形态复杂,并非单一均匀,肿瘤组织有明显的细胞和组织异型性,b值与组织信号强度衰减并不呈单指数模型(线性)关系;其次,小b值DWI成像,组织信号衰减与组织血流灌注相关。1986年Le Bihan等首次提出了基于体素内不相干运动(intravoxel incoherent motion,IVIM)的DWI成像,该技术采用多b值扫描,通过双指数模型计算反映组织扩散和微循环血流灌注的参数,且无需使用外源性对比剂。目前, IVIM在肿瘤疾病中的临床应用已经成为研究的热点,笔者对IVIM在人体肿瘤影像诊断中的应用进展进行综述。
出处 《中华放射学杂志》 CAS CSCD 北大核心 2016年第7期553-555,共3页 Chinese Journal of Radiology
作者简介 通信作者:牛金亮,Email:sxlscjy@163.com
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参考文献33

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二级参考文献73

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