摘要
目的:探讨肝移植术后胆道非吻合口狭窄的诊断及治疗方法。方法:回顾分析肝移植术后发生胆道非吻合口狭窄患者的资料,对比非吻合口狭窄的诊断和治疗方法,探讨诊疗的最佳方法。结果:肝移植术后非吻合口狭窄主要表现为胆红素、谷氨酰转肽酶升高及反复发作的胆系感染,与对照组(肝移植术后无胆道狭窄的患者)差异有统计学意义(P<0.01)。患者通过MRCP、CT及ERCP能明确诊断,通过内镜下胆道支架植入术、内镜下球囊扩张、经皮肝穿刺胆管引流术(PTCD)能起到治疗目的,提高患者生存质量。结论:胆道非吻合口狭窄为肝移植术后常见并发症,诊断明确后可采用内镜下胆道支架植入术、内镜下球囊扩张、PTCD等手段治疗。
Objective： To study the diagnosis and treatment of non-anastomotic biliary stricture after liver transplantation. Methods： Retrospective analysis the patients, data after liver trans- plantation in biliary anastomotic stenosis, compared the method in the diagnosis and treatment of anastomotic stenosis, to explore the best way for diagnosis and treatment. Results： The non-anastomotic biliary stricture after liver transplantation mainly of elevated bilirubin, GGT and recurrent biliary infection, and the control group（patients without biliary stricture after liver transplantation）difference was statistically significant（P〈 0.01）. Patients by MRCP CT, ERCP, could clear diag-nosis, through endoscopic biliary stent implantation, endoscopic balloon expansion, percutaneous transhepatic cholangiography drainage could have therapeutic purposes, improving the quality of survival. Conclusion： Non-anastomotic biliary stricture after liver transplantation is a common complication after liver transplantation, Endoscopic biliary stent implantationendoscopic biliary stent implantation,and percutaneous transhepatic cholangiography drainage（PTCD） can be used after diagnostic clear.
出处
《中国现代普通外科进展》
CAS
2016年第5期385-389,共5页
Chinese Journal of Current Advances in General Surgery
关键词
肝移植
胆道非吻合口狭窄
病因
诊断
治疗
Liver transplantation, Non-anastomotic biliary stricture- Pathogenesis, Diagnosis
作者简介
史育仪（1987-10-），男，山东诸城人，硕士研究生，研究方向：普通外科学。E-mail：bingshi666@163．com
[通讯作者]李森（1956-03-），男，河北唐山人，主任医师，教授，硕士生导师，研究方向：肝胆外科。E—mail：Lisen988@sohu．com
