摘要
目的探讨硝氯酚中毒的发生机制、临床表现及诊治要点。方法对硝氯酚中毒1例的临床资料进行回顾性分析。结果本例因服用硝氯酚后7 h就诊(入院前已在当地医院予洗胃、导泻治疗),入院时伴恶心呕吐,无呕血、抽搐及意识不清,无发热及视物模糊,查血常规、血生化均正常;入院第3天出现频发室性早博,全身肌肉酸痛,发热,体温最高达40.8℃;第4天出现视力下降,并相继出现肝肾功能、心肌酶异常,予物理降温、补液、能量合剂、脱水、糖皮质激素、营养神经及心肌、护肝肾等治疗;入院第14天视力恢复正常;第16天体温及血生化指标好转出院。结论硝氯酚中毒临床少见,且临床表现缺乏特征性,及时洗胃、导泻,预防二次中毒是治疗成功的关键。
Objective To explore the pathology of niclofelan poisoning,clinical manifestation and main points of diagnosis and treatment. Methods 1 case of niclofelan poisoning was enrolled in this study and the clinical data were retrospectively analyzed. Results This patient came to see the doctor after he had taken the medicine for 7 hours（ gastric lavage and catharsis had been made in a local hospital）. Upon admission,the patient started to nauseate and vomit but with no hematemesis,no twitch,no confusion,no fever and no blurring of vision,and the results of blood test were normal. On the 3rd day after admission,frequent ventricular premature beats appeared on the ECG monitor. The patient started to complain of fatigue,aching muscles,fever（ the temperature was up to 40. 8℃）. There appeared abnormal liver and renal functions and myocardial enzymes. Diminution of vision occurred on D4. Physical cooling,fluids,energy compounds,dehydration,glucocorticoids,neuro nutrition and myocardial nutrition,protection of liver and renal function were administered in the patient. On D4,the vision returned to normal,body temperature and blood biochemical indexes improved on D16 and the patient was discharged from hospital. Conclusion Niclofelan poisoning is clinically rare. Its clinical manifestations lack specificity. Gastric lavage and catharsis as early as possible and preventing secondary poisoning are key to successful treatment.
出处
《临床误诊误治》
2016年第6期20-22,共3页
Clinical Misdiagnosis & Mistherapy
关键词
硝氯酚
中毒
误诊
急救
Niclofelan
Poisoning
Misdiagnosis
First aid
作者简介
通讯作者：侯云生，电话：0311—87978639
