摘要
目的：制备白芍饮片标准汤剂,并进行质量标准研究。方法：以水为溶剂,以标准化工艺制备标准汤剂,采用UPLCDAD法测定芍药苷含量,并进行转移率、出膏率计算及指纹图谱研究。结果：10批次白芍样品制成的标准汤剂中芍药苷含量为1.69-2.60 mg/m L,转移率为60.47%-85.16%,平均转移率为71.62%,标准偏差为8.74%。出膏率范围为19.00%-26.50%,平均出膏率为21.89%,标准偏差为2.51%。指纹图谱共有峰11个,确认5个,分别是：氧化芍药苷、儿茶素、芍药内酯苷、芍药苷、苯甲酰芍药苷。结论：本方法处理样品简单,重复性好,可用于白芍标准汤剂的制备及质量标准研究。
Objective To study the preparation and quality standard of the standard decoction of paeonia lactiflora. Methods： Thestandard decoction of paeonia lactiflora was preparated with water by using standardization method and the content of peoniflorlnwas determined by UPLC-DAD. Then calculate the transfer rate, the rate of extractum and carry on the research of fingerprint. Re-suits：The content of paeoniflo-rin in 10 batches of standard decoction of paeonia lactiflora is 1.69 -2. 60 mg/mL,the transfer rateis 60.47% -85.16% ,the average transfer rate is 71.62% and the standard deviation is 8.74%. The rate of extractum is 19.00% - 26. 50% , the average yield is 21.89% and the standard deviation is 2. 51%. There were 11 common peaks ,5 of which were iden-tified, including oxypaeoniflorin, catechins, albiflorin, paeoniflorin and benzoylpaeoniflorin. Conclusion ： The method is simple withgood repeatability, and it can be used to study the preparation of the standard decoction of paeonia lacti-flora.
出处
《世界中医药》
CAS
2016年第5期753-757,共5页
World Chinese Medicine
基金
中国中医科学院综合性大平台项目(编号:Z2014003-05)
关键词
白芍
饮片
标准汤剂
指纹图谱
Paeonia lactiflora
Medicinal slices
Standard decoction
Fingerprint
作者简介
朱广伟，博士，助理研究员，研究方向：中药药效物质基础研究、中药药效组分评价体系研究，E-mail：gwzhu@icmm．ac．cn
通信作者：陈士林，博士研究生导师，主要从事中药资源学研究，Tel：（010）57203877，E-mail：slchen@icmm．ac．cn
