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后腹腔镜肾癌根治术后联合中药治疗的临床疗效及安全性研究 被引量:1

Efficacy and safety of retroperitoneal laparoscopic radical nephrectomy for renal cell carcinoma
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摘要 目的探讨采用后腹腔镜手术治疗肾癌的疗效及安全性。方法将68例肾癌患者分为两组,34例行后腹腔镜肾癌根治术,34例行开放肾癌根治术,术后给予全部患者口服中药汤剂;对比分析两组患者术中耗时、失血量,术后腹腔功能回复时间、下床活动时间、总住院时间和术后并发症等之间的差异。并对患者术前和术后淋巴细胞、C反应蛋白和白介素水平进行测定。结果腹腔镜术后组患者手术耗时明显较开放手术组短,失血量明显较开放手术组少,下床活动的时间明显较开放手术组早,住院时间明显较开放手术短,差异均有统计学意义(P<0.05);腹腔镜术后与开放手术后患者淋巴细胞计数、C反应蛋白、白介素水平均显著高于手术前,但腹腔镜组术后淋巴细胞计数、C反应蛋白、白介素水平均较开放手术组低,差异均有统计学意义(P<0.05)。腹腔镜组术后并发症发生率为8.82%,显著低于开放组并发率29.41%,两组比较差异具有统计学意义(P<0.05)。结论后腹腔镜肾癌根治术联合中药治疗肾癌是安全有效的,具有手术耗时短、创伤小、恢复快、并发症少等优势。 Objective To investigate the efficacy and safety of laparoscopic surgery in the treatment of renal cell carcinoma.Methods A total of 68 cases of renal cell carcinoma were divided into 2 groups:laparoscopic group(n=34)treated with retroperitoneal laparoscopic radical nephrectomy,and open surgery group(n=34)treated with open nephrectomy.After operation,all patients orally took Chinese medicine decoction.The operation time,blood loss,abdominal function recovery time,ambulation time,hospital stay,postoperative complications of the 2groups were recorded and compared.Preoperative and postoperative counts of lymphocytes,levels of C reactive protein and interleukin were also detected.Results The laparoscopic group had shorter operation time and hospital stay,less blood loss,and earlier ambulation than the open surgery group(all P0.05).The postoperative lymphocyte count,levels of C reactive protein and interleukin were significantly higher than the preoperative values in both groups(all P0.05);the values were lower in the laparoscopic group than in the open surgery group(all P0.05).The incidence of postoperative complications was 8.82% and29.41%in the laparoscopic group and open surgery group,with significant difference(P0.05).Conclusion Retroperitoneal laparoscopic radical nephrectomy is safe and effective in the treatment of renal cell carcinoma,with advantages of shorter operation time,less trauma,quicker recovery,less complications compared with open surgery.
出处 《国外医学(医学地理分册)》 CAS 2016年第2期141-144,共4页 Foreign Medical Sciences:Section of Medgeography
关键词 后腹腔镜 肾癌根治术 临床疗效 并发症 retroperitoneal laparoscope radical nephrectomy efficacy complications
作者简介 刘亚伯(1968-),男(汉族),大学本科,副主任医师.研究方向:泌尿外科学及男科疾病诊治.E—mail:1yb680830@126.com
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  • 1杨明山,王琳,李希明,吴吉涛,高振利,夏术阶.腹腔镜与开放肾癌根治术的临床效果比较(附102例报告)[J].山东医药,2006,46(21):40-41. 被引量:5
  • 2缪惠东,沈锋,葛劲超.后腹腔镜与开放性肾囊肿去顶术对比研究[J].交通医学,2007,21(2):152-153. 被引量:4
  • 3Heuer R, Gill IS, Guazzoni G, et al. A critical analysis of the actual role of minimally invasive surgery and active surveillance for kidney cancer[J]. Eur Urol, 2010,57(2) :223-232.
  • 4Eskicorapci SY, Teber D, Schulze M, et al. Laparoscopic radical nephrectomy: the new gold standard surgical treatment for localized renal cell carcinoma [ J]. ScientificWorldJournal, 2007, (7) :825-836.
  • 5Makhoul B, De La Taille A, Vordos D, et al. Laparoscopic radical nephrectomy for T1 renal cancer: the gold standard? A comparison of laparoscopic vs open nephrectomy [ J ]. BJU Int, 2004,93 ( 1 ) : 67 -70.
  • 6Clayman RV, Kavoussi LR, Soper NJ, et al. Laparoscopic nephreetomy: initial case report[J]. J Urol, 1991,146(2) :278-282.
  • 7Okegawa T, Noda H, Horie S, et al. Comparison of transperitoneal and retroperitoneal laparoscopic nephrectomy for renal cell carcinoma: a single center experience of 100 cases[ J ]. Int J Urol, 2008, 15 ( 11 ) :957-960.
  • 8Taue R, Izaki H, Koizumi T, et al. Transperitoneal versus retroperitoneal laparoscopic radical nephrectomy: a comparative study [ J 1. Int J Urol, 2009,16 ( 3 ) : 263-267.
  • 9Steinberg AP, Finelli A, Desai MM, et al. Laparoscopic radical nephrectomy for large ( greater than 7 cm, T2 ) renal tumors [ J ]. J Uml, 2004,172(6 Pt 1):2172-2176.
  • 10Clayman R V,Kavoussi L R,Soper N J,Dierks S M,Meretyk S,Darcy M D,et al.Laparoscopic nephrectomy:initial case report[J].J Urol,1991,146:278-282.

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