摘要
[目的]评价肿瘤全营养配方食品对放疗食管癌患者的临床应用及耐受情况。[方法]75例PG-SGA≥4分的放疗食管癌患者,进行营养补充肿瘤全营养配方食品(倍康素);28例患者采取口服补充途径,47例患者采用管饲补充途径;倍康素平均使用量为3.3罐/d(相当于1072.5kcal)。评估倍康素对食管癌患者营养状态、放疗副反应发生率、胃肠道症状发生率的影响。[结果]所有患者均按计划完成放疗,患者前白蛋白和转铁蛋白显著升高(P<0.05),总蛋白、白蛋白、白细胞、血红蛋白、血小板、C-反应蛋白检测值与放疗前相比无明显变化;胃肠道不良反应(恶心、呕吐、腹胀、腹泻、腹痛)发生率均较低。[结论]倍康素的应用有助于维持食管癌放疗患者的营养状况,且患者的耐受性较好。
[Purpose] To assess the effect of specific nutritional supplement in radiotherapy for esophageal cancer. [Methods] Esophageal cancer patients（PG-SGA ≥4）（n =75） with radiotherapy treatment were asked to have Ensource in addition to their normal food intake,28 cases via oral nutrition supplement and 47 cases through tube feeding. Patients completed the nutritional support with consuming a median of 3.3 cans（1072.5 kcal）. Specific serum protein fractions as potential useful tools to evaluate the nutritional status were determined. Incidences of complication with radiotherapy and gastrointestinal symptoms were recorded. [Results] All patients completed radiotherapy. Compared to before radiotherapy,the level of prealbumin and transferrin were increased significantly（P〈0.05）. Values of total protein,albumin,leukocytes,hemoglobin,platelets and C-reactive protein did not change significantly over the course. In addition,the incidence of the gastrointestinal tract symptom（nausea,vomit,bloating,diarrhea and abdominal pain） was low. [Conclusions] There is a potential usefulness of Ensource in the compliance of radiotherapy and nutritional profile in patients with esophageal cancer.
出处
《中国肿瘤》
CAS
2016年第6期491-494,共4页
China Cancer
关键词
肿瘤全营养配方食品
食管癌
放疗
营养不良
营养治疗
specific nutritional supplement
esophageal cancer
radiotherapy
malnutrition
nutritional therapy
作者简介
通讯作者：于雷,E-mail：yulei01578@163.com
