摘要
目的回顾分析住院患者梅毒螺旋体抗体及相关传染性标志物检测结果,为梅毒的防治提供依据和意见。方法选取2014年1月至12月永嘉县人民医院11 862名住院患者,进行抗梅毒螺旋体（TP）抗体、乙型肝炎病毒表面抗原（HBsAg）、抗丙型肝炎病毒（HCV）抗体和抗人类免疫缺陷病毒（HIV）抗体检测。按照不同性别、年龄段、科室和疾病类型进行抗TP抗体阳性率、HBsA g阳性率、抗HCV抗体阳性率、抗HIV抗体阳性率的比较。结果抗TP抗体确诊阳性246例,阳性率2.07%,男性阳性率为2.34%,女性阳性率为1.80%,男女性别差异具有统计学意义（χ~2=4.401,P=0.036）。抗TP抗体阳性率在31~45岁组最高,为2.51%,科室方面,骨科最高,为3.25%,产科最低,为0.94%。内科、外科、骨科患者不同疾病间阳性率不同。246例梅毒抗体阳性患者中,HBsAg阳性31例（占11.79%）、抗HCV抗体阳性4例（占1.63%）、抗HIV抗体阳性1例（占0.41%）。结论该院住院患者梅毒抗体阳性率具有性别、年龄和科室病种差异,且阳性者合并高HBsA g和抗HCV抗体阳性率,须加强监测和护理,防止院内传播及患者间交叉感染。
Objective To review and analyze the results of antibody detection of syphilis and related infectious markers in hospitalized patients,and to provide evidence for the prevention and treatment of syphilis.Methods 11 862 hospitalized patients were selected in Yong jia people＇s hospital from January to December 2014,and all the patients＇ anti Treponema pallidum（TP） antibody,hepatitis B virus surface antigen（HBsA g）,anti- hepatitis C virus（HCV） antibody and anti- human immunodeficiency virus（HIV） antibody were tested.The comparison of the positive rate of syphilis antibody was done statistics according to the distribution of different sex,age,and department.Results There were 246 in- patients diagnosed as positive cases,and the positive rate was 2.07%.The rate of male and female were 2.34% and 1.80% respectively.The difference between male and female had statistical significance（χ~2= 4.401,P = 0.036）.The group of age 31~45 years had the highest positive rate.The highest department＇s positive rate was a department of orthopedics（3.25%）,and the lowest positive rate was in the department of obstetrics（0.94%）.There positive rate between the diseases of internal medicine,surgical,orthopaedics department among the TPPA positive patients were different.The cases of positive HBsA g,positive HCV,and positive HIV were 31（11.79%）,4（1.63%）,and 1（0.41%） in the 246 positive TPPA patients,respectively.Conclusions The positive rate of syphilis antibody was different in gender,age and department diseases,and combined with the high positive rate of HBsA g,anti- HCV antibody,and anti- HIV antibody.Monitoring and nursing should be strengthened to prevent hospital communication and cross- infection among patients.
出处
《现代预防医学》
CAS
北大核心
2016年第11期2106-2109,共4页
Modern Preventive Medicine
关键词
梅毒
传染性标志物
抗体
效价
回顾性分析
Syphilis
Infectious markers
Antibody
Titer
Retrospective analysis
作者简介
周腾坚（1985-），男，本科，主管检验师，研究方向：微生物学检验
通讯作者：杜季梅，E-mail：djm@wmu．edu．cn
