摘要
目的:探讨降钙素原(PCT)与超敏C反应蛋白(hs-CRP)检测在慢性支气管炎急性加重期病情评估的临床价值。方法:选择住院治疗的慢性支气管炎急性加重期患者50例作为观察组,另选取同期在笔者所在医院进行常规体检的中老年人40例作为对照组。分别测定对照组及观察组治疗前后PCT与hs-CRP浓度。结果:治疗前观察组PCT与hs-CRP浓度均显著高于对照组,差异有统计学意义(P<0.05);治疗后观察组PCT与hs-CRP浓度显著低于治疗前,差异有统计学意义(P<0.05),但与对照组比较,差异无统计学意义(P>0.05);线性相关分析PCT与hs-CRP浓度呈正相关(r=0.825,P<0.01)。结论:慢性支气管炎急性加重期患者PCT与hs-CRP浓度明显上升,治疗后患者的PCT与hs-CRP浓度显著下降,可为判断病情严重性及评估治疗效果提供参考。
Objective：To discuss the clinical value of procalcitonin（PCT） and hypersensitive C-reactive protein（hs-CRP） in detection of acute exacerbation of chronic bronchitis.Method：Fifty patients with acute exacerbation of chronic bronchitis were selected as the observation group,and 40 middle aged and elderly people in our hospital for physical examination were selected as the control group,data of PCT and hs-CRP were respectively detected in the control group and the observation group before after treatment.Result：The concentrations of PCT and hs-CRP in the observation group were significantly higher than those in the control group,the differences were statistical significance（P〈0.05）.concentrations of PCT and hs-CRP in the observation group were significantly lower than those before treatment,the differences were statistical significance（P〈0.05）,but compared with the control group,there was no statistical significance（P〉0.05）,linear correlation analysis showed positive correlation between concentration of PCT and hs-CRP（r=0.825,P〈0.01）.Conclusion：Concentrations of PCT and hs-CRP are significantly increased before treatment and significantly decreased after treatment in patients with acute exacerbation of chronic bronchitis,which can provide a reference for judging the severity of the disease and evaluate the treatment effect.
出处
《中外医学研究》
2016年第14期25-26,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
降钙素原
超敏C反应蛋白
慢性支气管炎
Procalcitonin
Hypersensitive C-reactive protein
Chronic bronchitis
