摘要
目的研究高血压患者血压升高程度与客体工作记忆损伤相关性。方法选取52例首发高血压患者(试验组)和48例健康对照组(HC组)作为研究对象。用20幅图片测量客体短期记忆,用客体工作记忆测试作为客体工作记忆评定工具,并研究血压与客体记忆之间的相关性。结果排除焦虑及抑郁情绪情况下,试验组在视觉客体工作记忆任务的正确率和反应时间[(77.69±11.21)%、(1 494.92±238.36)ms]均差于HC组[(83.37±7.75)%、(1 397.49±240.54)ms],差异有统计学意义(P<0.05)。试验组的短期客体记忆得分[(10.73±2.86)分]差于HC组[(12.05±3.27)分],差异有统计学意义(P<0.05);试验组收缩压水平与视觉客体工作记忆正确率及呈短期工作记忆得分负相关(r=-0.590、-0.574,P<0.01)。结论首发高血压患者已经存在客体记忆方面的损伤,客体记忆损伤程度与收缩压水平密切相关。
Objective To investigate the correlation between the degree of blood pressure and the injury of the working memory in first-episode hypertension.Methods A total of 52 patients with first-episode hypertension were compared with matched48 health controls.Twenty picture were used to measure short-term object memory,the visual-object working memory task were used to measure object working memory.Then we compared the relationship between blood pressure and memory function.Results The correct rate and reaction time of visual-object working memory task in patients[（77.69±11.21）%,（1 494.92±238.36）ms]were worse than healthy controls[（83.37±7.75）%,（1 397.49±240.54）ms,P〈0.05],scale of short-term memory in the patients[（10.73±2.86）score]were worse than that of the healthy controls[（12.05±3.27）score,P〈0.05];systolic blood pressure in patients was negative correlation to correct rate of visual-object working memory test and scale of short-term memory（r=-0.590,-0.574,P〈0.01）.Conclusion Patients with first-episode hypertension might have impairment in object memory;the deficit degree of object memory for patients is closely related to systolic blood pressure.
出处
《重庆医学》
CAS
北大核心
2016年第14期1927-1929,共3页
Chongqing medicine
关键词
高血压
认知
记忆
hypertension
cognition
memory
作者简介
葛君（1983一），主治医师，本科，主要从事心血管疾病研究。
通讯作者，E—mail：wangbangning@medmail．com.cn.
