摘要
目的对肌钙蛋白I与N端脑钠肽原在慢性心衰患者危险预测中的应用价值进行分析讨论。方法选择我院2013年9月-2015年9月间37例慢性心衰患者,将其作为观察组,同时随机选取心功能正常入院患者37例,将其作为对照组,所有患者入院后都进行肌钙蛋白I与N端脑钠肽原检测,比较两组患者肌钙蛋白I与N端脑钠肽原水平。结果观察组患者肌钙蛋白I水平平均为(4.5±3.0)ng/ml,明显高于对照组,患者N端脑钠肽原水平平均为(769.5±322.5)pg/ml,同样高于对照组,两组比较存在明显差异,P<0.05。心功能评级为Ⅱ级的患者,肌钙蛋白I、N端脑钠肽原水平最低,心功能评级为Ⅳ的患者,肌钙蛋白I、N端脑钠肽原水平最高,三个组比较存在明显差异,P<0.05。结论肌钙蛋白I与N端脑钠肽原能够对慢性心衰患者的病情进行预测,提示患者病情严重程度。
Objective To investigate the value of troponin I and N-terminal pro-brain natriuretic peptide in predicting the risk of chronic heart failure. Methods A total of 37 patients with chronic heart failure who were treated in our hospital from September 2013 to September 2105 were enrolled as observation group. Another 37 patients with normal cardiac function who were admitted to our hospital were enrolled as control group. Troponin I and N-terminal pro-brain natriuretic peptide levels were determined for both groups after admission and compared between the two groups. Results Compared with the control group, the observation group had significantly higher mean levels of troponin I （4.5±3.0ng/ml） and N-terminal pro-brain natriuretic peptide （769.5±322.5pg/ml） （P〈 0.05）. The patients with cardiac function class II had the lowest levels of troponin I and N-terminal pro-brain natriuretic peptide, and those with cardiac function class IV had the highest levels of troponin I and N-terminal pro-brain natriuretic peptide. The levels of troponin I and N-terminal pro-brain natriuretic peptide showed significant differences across the three groups （P〈0.05）. Conclusion Troponin I and N-terminal pro-brain natriuretic peptide can be measured to predict the condition of patients with chronic heart failure and suggest the severity of their condition.
出处
《心血管病防治知识（学术版）》
2016年第4期70-72,共3页
Prevention and Treatment of Cardiovascular Disease
关键词
肌钙蛋白TI
N端脑钠肽原
慢性心衰
Troponin I
N-terminal pro-brain natriuretic peptide
Chronic heart failure
作者简介
朱湘慧，1973年生，男，汉族，湖南人，本科学历，主要从事急诊及重症医学工作。
