摘要
为探讨鸡FABP2基因多态性对肉鸡生长和体组成性状的影响,以东北农业大学F2资源群体为试验材料,对鸡FABP2基因3个多态性位点（c.601A＞T,c.1018C＞T和c.3267G＞A）利用基质辅助激光解析电离飞行时间质谱（MALDI-TOF-MS）方法进行基因型分析,利用3个多态性位点基因型信息构建单倍型并分析单倍型与鸡生长和体组成性状的相关性.结果：FABP2基因3个多态性位点构建的单倍型对鸡2～12周龄体重、龙骨长和4周龄跖骨长有显著影响（P＜0.05）;对8和10周龄跖骨长、跖骨围、胸宽、腹脂率、胫骨长有一定的影响（P＜0.2）.由此推断：影响鸡体重和骨骼性状的QTL可能位于此单倍型区域内,ACG单倍型为提高体重和骨骼性状的有利单倍型.
This study aimed to investigate the effects of polymorphisms of FABP2 gene on growth and body composition traits in broiler chickens. MALDI-TOF-MS method was used to detect the polymorphisms of FABP2 gene and the genotypes of 3 SNPs （c.601A〉T, c.1018C〉T and c.3267G〉A）were obtained in Northeast Agricultural University F2 resource population. Haplotypes were constructed using their genotypes,and the association analysis between the haplotypes and the growth and body composition traits was performed. The association analysis showed that haplotypes were significantlyassociated with body weight （BW）at 6 to 12 weeks of age,keel length （KeL）and metatarsus length （MeL）at 4 weeks of age （P〈0.05）,and suggestively significantly associated with metatarsus length （MeL）at 8 to 10 weeks of age,metatarsus circumference （MeC）,chest width （ChWi）,abdominal fat percentage （AFP）, shank bone length （ShL） in chickens （P〈0.2）. Therefore,it was concluded that the QTL affecting growth and development of body weight and skeleton traits in chickens might reside in the haplotype region and ACG might be favorite haplotype for improving body weight and skeleton traits in chickens.
出处
《中国家禽》
北大核心
2016年第8期5-9,共5页
China Poultry
基金
国家自然科学基金面上项目(31572394)
现代农业产业技术体系建设专项资金(CARS-42)
东北农业大学东农学者计划“学术骨干”项目(15XG13)
作者简介
通讯作者，E-mail：lihui@neau．edu．cn
shouzhiwang@126．com
