序贯器官衰竭估计评分预测严重感染预后的临床研究被引量：7

Clinical study of sequential organ failure assessment score in prediction of prognosis of patients with severe infections

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摘要目的探讨序贯器官衰竭估计（SOFA）评分对急诊严重感染患者预后的影响,为预测急诊严重感染患者预后提供理论指导。方法选取2013年2月-2015年2月于医院接受治疗的184例急诊严重感染患者作为研究对象,根据结局将患者分为两组,142例生存患者为观察组,42例死亡患者为对照组,两组患者均采用同样的抗感染治疗方式,计算两组患者在在入院72h后的各个阶段的SOFA评分,对比患者SOFA评分和病死率,对比两组患者入院前后的SOFA评分,对比两组患者身体器官和整体的SOFA评分情况;采用SPSS16.0软件对数据进行统计分析。结果 184例急诊严重感染患者在入院72h后的各个阶段SOFA评分和患者病死率之间存在关联,SOFA评分〈4时,患者病死率为0;SOFA评分为4～8分时,患者病死率为7.14%;SOFA评分为9～13分时,患者病死率为13.64%;SOFA评分为14～16分时,患者病死率为20.59%;SOFA评分〉16分时,患者病死率为100.00%,差异有统计学意义（P〈0.05）;观察组患者T0SOFA评分（入院时的评分）和T72SOFA评分（入院72h后的评分）明显低于对照组,两组比较差异有统计学意义（P〈0.05）;观察组患者损伤的器官个数评分为（2.9±1.2）分,对照组为（4.6±2.1）分,对照组高于观察组,对照组六大功能器官的评分也明显高于观察组的评分,两组差异有统计学意义（P〈0.05）。结论 SOFA评分能很好的预测急诊严重感染患者的预后,值得在临床推广应用。 OBJECTIVE To explore the impact of sequential organ failure assessment（SOFA）score on prognosis of emergency department patients with severe infections so as to provide theoretical basis for prediction of prognosis of the patients with severe infections.METHODS A total of 184 emergency department patients with severe infections who were treated from Feb 2013 to Feb 2015 were recruited as the study objects and divided into two groups according to the outcomes,142 patients who survived were assigned as the observation group,and 42 patients who died were set as the control group.Both groups received the same anti-infection therapy,the SOFA score of the two groups of patients was calculated at various stages after the admission for 72 hours,the SOFA score and mortality rate were compared,the SOFA score was compared between the two groups of patients before and after the admission,the SOFA score of body organs and the overall SOFA score were compared between the two groups of patients,and the statistical analysis of data was performed with the use of SPSS16.0software.RESULTS There was an association between the SOFA score and the mortality rate at the various stages after the 184 emergency department patients with severe infections were admitted for 72 hours,the mortality rate was 0when the SOFA score was less than 4,the mortality rate was 7.14% when the SOFA score varied from 4to 8points,the mortality rate was 13.64% when the SOFA score varied from 9to 13 points,the mortality rate was 20.59% when the SOFA score varied from 14 to 16points,the mortality rate was 100.00% when the SOFA score was more than 16 points,and there was significant difference（P〈0.05）.The T0 SOFA score（score at the admission）and T72 SOFA score（score after the admission for 72hours）were significantly lower in the observation group than those in the control group,and there was significant difference between the two groups（P〈0.05）.The score of the injured organs of the control group was（4.6±2.1）points,significantly higher than（2.9±1.2）points of the observation group;the score of the six functional organs of the control group was also significantly higher than that of the observation group（P〈0.05）.CONCLUSION The SOFA score can predict the prognosis of the emergency department patients with severe infections,and it is worthy to be promoted in the hospital.

作者朱峰刘超群任萍戚建巨周芸

机构地区宁波大学医学院附属医院急诊内科宁波国际旅行卫生保健中心

出处《中华医院感染学杂志》 CAS CSCD 北大核心 2016年第10期2257-2259,共3页 Chinese Journal of Nosocomiology

基金浙江省卫生厅基金资助项目(ZW-2010B030)

关键词序贯器官衰竭预测急诊严重感染预后临床研究 Sequential organ failure Prediction Emergency severe infection Prognosis Clinical study

分类号 R459.7 [医药卫生—急诊医学]

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