摘要
目的：评价氯己定全身洗浴对ICU患者导尿管相关性尿路感染的预防效果。方法：计算机检索Cochrane图书馆、Pubmed、Ovid Medline、EMbase、中国生物医学文献服务系统（CBM）、维普数据库（VIP）、中国期刊全文数据库（CNKI）以及万方数据库（Wan Fang Data）中关于氯己定全身洗浴用于预防ICU患者导尿管相关性尿路感染的随机对照试验、临床对照实验。2名研究者独立检索、筛查文献、提取数据、评价纳入文献的方法学质量并交叉核对后,采用Rev Man 5.3软件进行Meta分析、亚组分析。结果：共纳入8篇文献,2篇随机对照试验和6篇临床对照实验。Meta分析结果显示：与肥皂水擦浴相比,氯己定全身洗浴可以降低ICU患者导尿管相关性尿路感染的发生率[RR=0.76,95%CI（0.60~0.95）,P=0.02],差异具有统计学意义。结论：氯己定全身洗浴可以降低ICU患者导尿管相关性尿路感染的发生率,建议临床推广。
Objective： To evaluate the impact of body bathing with chlorhexidine solution on preventing catheter associated urinary tract infections in ICU. Methods： Electronic searches of databases were performed to identify relevant randomized controlled trials （RCTs） and clinical control studies （CCTs）. The databases used were Cochrane Library, PubMed, Medline/Ovid, EMbase, CBM, VIP, CNKI, and Wan Fang Data. Two reviewers independently screened potentially eligible articles, extracted data and assessed risk of bias. RevMan 5.3 software was used to perform Meta- analysis and sub-group analysis. Results：8 published studies were recruited for systematic review, which contained 2 RCTs and 6 CCTs. The results of Meta-analysis showed that, compared with non-medicated soap group, body bathing with chlorhexidine had significantly decreased the incidences of catheter associated urinary tract infection [RR=0.76, 95% CI （0.60-0.95）, P=0.02]. Conclusions： Total body bathing with chlorhexidine is associated with decreased catheter associated urinary tract infection rate in ICU.
出处
《中国护理管理》
CSCD
2016年第5期650-654,共5页
Chinese Nursing Management
关键词
氯己定
洗浴
重症监护病房
尿管相关性尿路感染
META分析
Chlorhexidine
Baths
Intensive Care Unit
Catheter-associated Urinary Tract Infection
Meta-analysis
作者简介
孙建华，本科，护师
通信作者：刘大为，博士，主任医师，主任，Email：dwliu98@163．com
